Ventipulmin® Syrup(clenbuterol HCl)
Autor Name: Boehringer Ingelheim Vetmedica, Inc.
Code Source: 0010-3017
Route of Administration: ORAL
- CLENBUTEROL HYDROCHLORIDE CLENBUTEROL : Active ingredient - basis of strength - 0.0725 mg in 1 mL
- 50 mL in 1 BOTTLE, PLASTIC
- 100 mL in 1 BOTTLE, PLASTIC
- 330 mL in 1 BOTTLE, PLASTIC
- 460 mL in 1 BOTTLE, PLASTIC
NADA 140-973, Approved by FDA
For oral use in horses only
CautionFederal law restricts this drug to use by or on the order of a licensed veterinarian.
CautionFederal law prohibits the extralabel use of this drug in food animals.
Each mL containsClenbuterol HCl 72.5 mcg
DescriptionClenbuterol (4-amino-alpha-[(tert-butylamino) methyl]-3, 5-dichlorobenzyl alcohol hydrochloride) is a beta-2-adrenergic agonist which provides bronchodilating properties as well as other effects, with minimum effect on the cardiovascular system. It is provided as a colorless, palatable syrup. Ventipulmin Syrup (clenbuterol hydrochloride) is antagonized by beta-adrenergic blocking agents.
IndicationsVentipulmin Syrup (clenbuterol hydrochloride) is indicated for the management of horses affected with airway obstruction, such as occurs in chronic obstructive pulmonary disease (COPD).
ContraindicationsVentipulmin Syrup antagonizes the effects of prostaglandin F 2 alpha and oxytocin. Ventipulmin Syrup should not be used in pregnant mares near term. Because tachycardia may occur, Ventipulmin Syrup should not be used in horses suspected of having cardiovascular impairment.
WarningThe effect on reproduction in breeding stallions and brood mares has not been determined. Treatment starting with dosages higher than the initial dose is not recommended.
Human WarningsNot for human use. Do not use in horses intended for human consumption. Keep out of the reach of children. In case of accidental ingestion, contact a physician immediately. Ingestion of Ventipulmin Syrup may cause undesirable reactions. Clenbuterol, like other beta adrenergic agonists, can produce significant cardiovascular effects in some people as evidenced by elevated pulse rate, blood pressure changes and/or ECG changes.
Dosage and AdministrationAdminister orally twice a day (b.i.d.). Initial dose is 0.5 mL/100 lbs body weight (0.8 mcg/kg) twice daily.
Dosage ScheduleInitial dosage: administer 0.5 mL/100 lbs (0.8 mcg/kg) for 3 days (6 treatments);
If no improvement, administer 1.0 mL/100 lbs (1.6 mcg/kg) for 3 days (6 treatments);
If no improvement, administer 1.5 mL/100 lbs (2.4 mcg/kg) for 3 days (6 treatments);
If no improvement, administer 2.0 mL/100 lbs (3.2 mcg/kg) for 3 days (6 treatments);
If no improvement, horse is non-responsive to clenbuterol and treatment should be discontinued.
Recommended duration of treatment at effective dose is 30 days. At the end of this 30-day treatment period, drug should be withdrawn to determine recurrence of signs. If signs return, the 30-day treatment regimen may be repeated. If repeating treatment, the step-wise dosage schedule should be repeated.
Dosage Calculation Chart
|Lbs. Body Weight||mL/treatment at 0.5 mL/100# (0.8 mcg/kg)||mL/treatment at 1.0 mL/100# (1.6 mcg/kg)||mL/treatment at 1.5 mL/100# (2.4 mcg/kg)||mL/treatment at 2.0 mL/100# (3.2 mcg/kg)|
|500 600 700 800 900 1000 1100 1200 1300 1400 1500 1600 1700 1800||2.5 3.0 3.5 4.0 4.5 5.0 5.5 6.0 6.5 7.0 7.5 8.0 8.5 9.0||5.0 6.0 7.0 8.0 9.0 10.0 11.0 12.0 13.0 14.0 15.0 16.0 17.0 18.0||7.5 9.0 10.5 12.0 13.5 15.0 16.5 18.0 19.5 21.0 22.5 24.0 25.5 27.0||10.0 12.0 14.0 16.0 18.0 20.0 22.0 24.0 26.0 28.0 30.0 32.0 34.0 36.0|
Directions for AdministrationRemove safety cap and seal; replace with enclosed plastic dispensing cap. Remove cover from dispensing tip and connect syringe (without needle). Draw out appropriate volume of Ventipulmin Syrup. Administer orally to the horse. Replace cover on dispensing tip to prevent leakage.
PrecautionThe safety cap should be placed on the bottle when not in use.
Adverse ReactionsMild sweating, muscle tremor, restlessness, urticaria and tachycardia may be observed in some horses during the first few days of treatment. May cause elevated creatine kinase (CK) serum levels. Ataxia was observed in 3 out of 239 horses (1.3%) in clinical studies. To report suspected adverse reactions, to obtain a Material Safety Data Sheet (MSDS), or for technical assistance, call 1-866-638-2226.
How SuppliedVentipulmin Syrup is available in 50 mL, 100 mL, 330 mL and 460 mL plastic bottles containing 72.5 mcg clenbuterol HCl per mL.
NDC 0010-3017-01 - 50 mL, NDC 0010-3017-02 - 100 mL
NDC 0010-3017-03 - 330 mL, NDC 0010-3017-04 - 460 mL
StorageStore at controlled room temperature 59-86 °F (15-30°C). Avoid freezing.
Ventipulmin is a registered trademark of Boehringer Ingelheim Vetmedica GmbH.
Boehringer Ingelheim Vetmedica, Inc.
St. Joseph, MO 64506 U.S.A.
Made in Mexico
330 mL Bottle Label
Picture of 330 mL Bottle Label.
330 mL Display Carton (Part 1)Front panel, side panel and bottom flap
Picture of front panel, side panel and bottom flap of 330 mL display carton.
330 mL Display Carton (Part 2)Back panel, second side panel and top flap
Picture of back panel, second side panel and top flap of 330 mL display carton.