Veterinary Drug Handbook (VDH) is the reference veterinarians turn to when they want an independent source of information on the drugs that are used in veterinary medicine today.

Doses - CHLORPHENIRAMINE MALEATE

Note: Contents of sustained-release capsules may be placed on food, but should not beallowed to dissolve before ingestion.

Dogs: Dog

a) 4 - 8 mg PO q12h (Kirk 1986)
b) 2 - 4 mg PO bid-tid (Morgan 1988)

Cats: Cat

a) For adjunctive treatment of feline miliary dermatitis: 2 mg PO q12h (Kwochka 1986)
b) 1 - 2 mg PO bid-tid (Morgan 1988)
Monitoring Parameters -
1) Clinical efficacy and adverse effects
Client Information/FDA Approval Status - Except in the combination products listed below, noveterinary-approved product is available. Chlorpheniramine is approved for use in humans; the oraldosage forms are either prescription or non-prescription agents, depending on the product'slabeling. The injectable products are prescription only.
Dosage Forms/Preparations - Veterinary-Approved Products:. None None as a single entity. This compound is also found inthe veterinary-approved (dogs, cats, horses) products Diathal® (Schering) and Azimycin®(Schering). Diathal® contains: chlorpheniramine maleate 10 mg/ml, procaine penicillin G 200, 000
U/ml, dihydrostreptomycin sulfate 250 mg/ml and diphemanil methylsulfate 25 mg/ml. Azimycin®contains: chlorpheniramine maleate 10 mg/ml, procaine penicillin G 200, 000 U/ml, dihydrostreptomycin sulfate 250 mg/ml, dexamethasone 0.5 mg/ml, and procaine HCl 20 mg/ml.

Human-Approved Products:

Chlorpheniramine Maleate Oral Tablets 2 mg (chewable), 4 mg, 8 mg (timed release), 12 mg(timed release) (OTC)
Chlorpheniramine Maleate Oral Syrup 2 mg/5 ml in 118 ml btls (OTC)
Chlorpheniramine Maleate Injection 10 mg/ml in 30 ml vials & 100 mg/ml in 10 ml vials; (Rx)
There are many registered trade names for chlorpheniramine; a commonly known product is Chlor-Trimeton® (Schering). Many combination products are available that combine chlorpheniramine with decongestants, analgesics, and/or antitussives.
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