Doses - CHLORPROMAZINE HCL
Dogs: 
a) 3.3 mg/kg PO once to 4 times daily; 1.1 - 6.6 mg/kg IM once to 4 times daily; 0.55 - 4.4 mg/kg IV once to 4 times daily (Kirk 1986) b) As an antiemetic: 0.5 mg/kg IM q8h; 1 mg/kg per rectum q8h (DeNovo 1986)
c) As a sedative/restraining agent: 3 mg/kg PO q12h; 0.5 mg/kg IM or IV q12h (Davis1985b)
d) As a preanesthetic: up to 1.1 mg/kg IM 1 - 1.5 hours prior to surgery (Booth 1988a)
e) For tranquilization: 0.8 - 2.2 mg/kg PO bid-tid
As an antiemetic: 0.05 mg/kg IV tid-qid or 0.5 mg/kg SQ once to 4 times daily.
For irritable colon syndrome: 0.5 mg/kg IM once to 3 times daily
As a muscle relaxant during tetanus: 2 mg/kg IM bid (Morgan 1988)
f) As an adjuctive treatment for amphetamine toxicosis: 10 - 18 mg/kg IV (Dumonceaux1995)
g) As an antiemetic: 0.2 - 0.4 mg/kg SubQ q8h (Washabau and Elie 1995)
Cats: 
a) 3.3 mg/kg PO once to 4 times daily; 1.1 - 6.6 mg/kg IM once to 4 times daily; 0.55 - 4.4 mg/kg IV once to 4 times daily (Kirk 1986) b) As an antiemetic: 0.5 mg/kg IM q8h (DeNovo 1986)
c) As a sedative/restraining agent: 3 mg/kg PO once daily; 0.5 mg/kg IM or IV once daily(Davis 1985b)
d) As a preanesthetic: up to 1.1 mg/kg IM one to one and one-half hours prior to surgery(Booth 1988a)
e) As an antiemetic: 0.2 - 0.4 mg/kg SubQ q8h (Washabau and Elie 1995)
Cattle: 
a) Premedication for catle undergoing standing procedures: Up to 1 mg/kg IM (maycause regurgitation if animal undergoes general anesthesia) (Hall and Clarke 1983) b) 0.22 - 1.0 mg/kg IV; 1.0 - 4.4 mg/kg IM (Howard 1986)
Horses: Note: Because of side effects (ataxia, panic reaction) this drug is not recommended foruse in horses; use acepromazine or promazine if phenothiazine therapy is desired.
Swine: 
a) Premedication: 1 mg/kg IM (Hall and Clarke 1983) b) 0.55 - 3.3 mg/kg IV; 2 - 4 mg/kg IM (Howard 1986)
c) Restraint: 1.1 mg/kg IM (effects are at peak in 45-60 minutes);
Prior to barbiturate anesthesia: 2 - 4 mg/kg IM (Booth 1988a)
Sheep & Goats:
a) 0.55 - 4.4 mg/kg IV, 2.2 - 6.6 mg/kg IM (Lumb and Jones 1984) b) Goats: 2 - 3.5 mg/kg IV q5-6h (Booth 1988a)
Monitoring Parameters -
Client Information - Avoid getting solutions on hands or clothing as contact dermatitis may develop. May discolor the urine to a pink or red-brown color; this is not abnormal.
Dosage Forms/Preparations - Veterinary-Approved Products: None
Human-approved Products:
Chlorpromazine Tablets 10 mg, 25 mg, 50 mg, 100 mg, 200 mg; Thorazine® (SKF); Generic;(Rx)
Chlorpromazine Extended-release Capsules 30 mg, 75 mg, 150 mg, 200 mg, 300 mg;
Thorazine® Spansule®(SKF); (Rx)
Chlorpromazine Oral Solutions: 2 mg/ml (syrup) in 120 ml bottles; 30 mg/ml (concentrate) in 120 ml bottles, gallons; 100 mg/ml (concentrate) in 60 and 240 ml bottlesThorazine® (SKF) ;
Generic; (Rx)
Rectal suppositories 25 mg, 100 mg (as base); Thorazine® (SKF); (Rx)Injection 25 mg/ml in 1 & 2 ml amps and cartridges and 10 ml vials; Thorazine®(SKF);Ormazine® (Hauck); Generic; (Rx)