Doses - EPHEDRINE SULFATE

Dogs:

For treatment of bronchospasm:
a) For maintenance therapy: 1 - 2 mg/kg PO q8-12h (McKiernan 1992)
b) 2 mg/kg PO q8-12h (Bonagura 1994)
For treatment of urinary incontinence responsive to adrenergic drugs:
a) 4 mg/kg or 12.5 - 50 mg PO per dog q8-12h. (Papich 1992)
b) 5 - 15 mg PO q8h (Labato 1994)

Cats:

For treatment of bronchospasm:
a) For emergency treatment 2- 5 mg PO (McKiernan 1992)
For treatment of urinary incontinence responsive to adrenergic drugs:
a) 2 - 4 mg/kg PO q8-12h. (Papich 1992)
b) 2 - 4 mg PO q8h (Labato 1994)
Monitoring Parameters - 1) Clinical effectiveness; 2) Adverse effects (see above)
Client Information - For this drug to be effective, it must be administered as directed by theveterinarian; missed doses will negate its effect. It may take several days for the full benefit of thedrug to take place. Contact veterinarian if the animal demonstrates ongoing changes in behavior(restlessness, irritability) or if incontinence persists or increases.
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products: None

Human-Approved Products:

Ephedrine Sulfate Oral Capsules 25 mg (OTC), 50 mg (Rx); generic
Ephedrine Sulfate Injection 25 mg/ml in 1 ml amps
Ephedrine Sulfate Injection 50 mg/ml in 1 ml amps, 10 ml vials and 10 ml disposable syringes;
Ephedrine Sulfate® (Lilly); generic (Rx)