Doses - ETHACRYNIC ACID

Dogs & Cats:

a) 0.2 - 0.4 mg/kg IM or IV q4-12h (Allen, Pringle et al. 1993)
Monitoring Parameters - 1) Serum electrolytes, BUN, creatinine, glucose; 2) Hydration status; 3)
Blood pressure, if indicated; 4) Symptoms of edema, patient weight, if indicated; 5) Evaluation ofototoxicity, particularly with prolonged therapy or in cats
Client Information - Recommend to administer dosage with meals when possible. Clients shouldcontact veterinarian if symptoms of water or electrolyte imbalance occur. Symptoms such asexcessive thirst, lethargy, lassitude, restlessness, oliguria, GI distress or tachycardia may indicateelectrolyte or water balance problems.
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products: None

Human-Approved Products:

Ethacrynic acid Oral Tablets 25 mg, 50 mg; Edecrin® (Merck) (Rx)
Ethacrynate Sodium Powder for Injection (for IV use only) equiv. to 50 mg ethacrynic acid/50ml vial; Edecrin Sodium® (Merck); (Rx)