Veterinary Drug Handbook (VDH) is the reference veterinarians turn to when they want an independent source of information on the drugs that are used in veterinary medicine today.


Doses - GLYCOPYRROLATE

Dogs:

As an adjunct to anesthesia:
a) 0.011 mg/kg IV, IM, or SQ (Package Insert - Robinul®-V, Robins)
b) 0.01 - 0.02 mg/kg SQ or IM (Bellah 1988)
For adjunctive therapy of bradyarrhythmias:
a) 0.011 mg/kg IV or IM (Russell and Rush 1995)
To reduce hypersialism:
a) 0.01 mg/kg SQ prn (Krahwinkel 1988)

Cats:

As an adjunct to anesthesia:
a) 0.011 mg/kg IM, for maximum effect give 15 minutes prior to anesthetic administration(Package Insert - Robinul®-V, Robins)
For bradyarrhythmias:
a) 0.005 - 0.01 mg/kg IV or IM, 0.01 - 0.02 mg/kg SQ (Tilley and Miller 1986)

Rabbits & Rodents:

As adjunct to anesthesia: 0.01 - 0.02 mg/kg SubQ as need (Huerkamp 1995)

Horses:

For treatment of bradyarrhythmias due to increased parasympathetic tone:
a) 0.005 mg/kg IV (Muir and McGuirk 1987a)
As a bronchodilator:
a) Initially, 2 -3 mg IM bid-tid for a 450 kg animal (Beech 1987)
Monitoring Parameters - Dependent on route of administration, dose, and reason for use. See theatropine monograph for more information.
Client Information - Parenteral glycopyrrolate administration is best performed by professionalstaff and where adequate cardiac monitoring is available. If animal is receiving glycopyrrolatetablets, allow animal free access to water and encourage drinking if dry mouth is a problem
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products:
Glycopyrrolate for Injection 0.2 mg/ml in 20 ml vials; Robinul®-V (Veterinary - 20 ml vial only);(Fort Dodge) (Rx) Approved for use in dogs and cats.

Human-Approved Products:

Glycopyrrolate Tablets 1 mg & 2 mg; Robinul® & Robinul Forte® (2 mg) (Robins); Generic;(Rx)
Glycopyrrolate for Injection 0.2 mg/ml in 1, 2, 5, & 20 ml vials; Robinul® (Robins); Generic;(Rx)
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