Doses - MECHLORETHAMINE HCL

Dogs:

For the adjunctive treatment of lymphoreticular neoplasms or with intracavitary administrationfor treating pleural and peritoneal effusions:
a) 5 mg/m2 IV or intracavitary; repeat prn. (Jacobs, Lumsden et al. 1992)
Monitoring Parameters - 1) CBC with platelets at least every 1-2 weeks until stable; then every 3months; 2) Liver function tests; initially before starting treatment and then every 3-4 months; 3)
Injection site for signs of extravasation
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products: None

Human-Approved Products:

Mechlorethamine Powder for Injection 10 mg; Mustargen® (Merck); (Rx)