Doses - MECLOFENAMIC ACID

Dogs:

For sedation/analgesia:
a) 750 mcg (0.75 mg)/m2 body surface area IV or 1000 mcg (1 mg)/m2 body surface area IM. Allow to rest quietly for 15 minutes after injection. Practically, the following dosingtable may used:
(Package Insert; Domitor®¯Pfizer)
b) 10 - 40 mcg/kg IM; higher doses do not cause greater sedation, but increase the duration of effect (McGrath and Ko 1997a)
Cats: Caution not approved for this species.
For sedation/analgesia:
a) 40 - 80 mcg/kg IM; higher doses do not cause greater sedation, but increase the durationof effect (McGrath and Ko 1997a)
Monitoring Parameters - Level of sedation and analgesia; heart rate; body temperature.
Additionally, heart rhythm, blood pressure, respiration rate and pulse oximetry should be considered, particularly in higher risk patients if the drug is to be used.
Client Information - This drug should be administered and monitored by veterinary professionalsonly. Clients should be made aware of the potential adverse effects associated with its use, particularly in dogs at risk (older, preexisting conditions).
Dosage Forms/Preparations/FDA Approval Status - Veterinary-Approved Products:
Medetomidine HCl for Injection 1 mg/ml in 10 ml multidose vials; Domitor® (Pfizer); (Rx)
Approved for use in dogs.