Doses - MORPHINE SULFATE

Dogs:

For heartworm prevention: 3 mcg/kg PO once monthly. (Package Insert-ProHeart®); Fort
Dodge)

Cattle:

For labeled indications: 1 ml (5 mg)/10 kg (22 lb) BW applied directly to the hair and skinalong the top of the back from the withers to the base of the tail. Application should bemade to healthy skin avoiding mange scabs, skin lesions or extraneous foreign matter.(Label Directions¯Cydectin®; Fort Dodge)

Horses:

For labeled indications: 0.4 mg/kg BW. Administer gel by inserting the syringe applicatorinto the animal's mouth through the interdental space and depositing the gel in the back ofthe mouth near the base of the tongue. Once the syringe is removed, the animal's headshould be raised to insure proper swallowing of the gel. Horses weighing more than 1150lb require additional gel from a second syringe. (Label Directions¯Quest®; Fort Dodge)
Dosage Forms/Preparations/FDA Approval Status -
Moxidectin Oral Tablets 30 mcg, 68 mcg, or 136 mcg; ProHeart® (Fort Dodge); (Rx).
Approved for use in dogs 8 weeks or older.
Moxidectin 0.5% (5 mg/ml) Pour-On for Cattle in 500 ml, 1 L and 2.5 L containers. Cydectin®(Fort Dodge); (OTC). Approved for use in cattle; not to be used in female dairy cattle ofbreeding age. No meat withdrawal times required, but FDA has established tolerances of 50ppb and 200 ppb for parent moxidectin in muscle and liver, respectively, of cattle.
Moxidectin Oral Gel containing 20 mg/ml in 11.3 g syringes (sufficient to treat one 1150 lbhorse); Quest® (Fort Dodge) (OTC). Approved for use in horse or ponies not intended for food purposes.