Doses - AMPROLIUM HYDROCHLORIDE

Dogs:

For coccidiosis:
a) 100 - 200 mg/kg PO in food or water for 7-10 days. (Morgan 1988), (Kirk 1989), (Greene 1984)
b) Prophylaxis: 30 ml of 9.6% solution in one gallon (3.8 L) of drinking water or (notboth) 1.25 grams of 20% powder in food to feed 4 pups daily. Give as sole source offood or water for 7 days prior to shipping. Bitches may be given medicated water (asabove) as the sole source of water for 10 days prior to whelping. (USPC 1989)
c) Prophylaxis: 0.075% solution as drinking water (Matz 1995)

Cattle:

For coccidiosis:
a) Treatment: 10 mg/kg PO for 5 days; 5 mg/kg for 21 days for prophylaxis. (Todd,
Dipietro, and Guterbock 1986)

Swine:

For coccidiosis:
a) Treatment: 25 - 65 mg/kg PO once or twice daily for 3-4 days. (Todd, Dipietro, and Guterbock 1986)
b) 100 mg/kg/day in food or water. (Howard 1986)

Sheep & Goats:

For coccidiosis:
a) Lambs: 55 mg/kg daily PO for 19 days. (Todd, Dipietro, and Guterbock 1986)
Birds: a) For coccidiosis in pet birds: 2 ml (using the 9.6% solution)/gallon of water for 5 days or longer. Cages should be steam cleaned to prevent reinfection. Supplement diet with B vitamins. Some strains resistant in Toucans and Mynahs. (Clubb 1986)
For chickens (broilers or layers), turkeys, and pheasants: Refer to individual product instructions.
Monitoring Parameters -
1) Clinical efficacy
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products:
Amprolium 1.25% Medicated Crumbles for Top Dressing in 50 lb bags.; Corid® 1.25%
Crumbles (MSD-AgVet); (OTC) Approved for use in calves. Slaughter withdrawal = 24hours.
Amprolium 9.6% (96 mg/ml) Oral Solution; Corid® 9.6% Oral Solution (MSD-AgVet); (OTC)
Approved for use in calves. Slaughter withdrawal = 24 hours
Amprolium 20 % Soluble Powder; Corid® 20% Soluble Powder (MSD-AgVet); (OTC)
Approved for use in calves. Slaughter withdrawal = 24 hours
There are many combination products (medicated feeds, feed additives) containing amprolium withother therapeutic agents. These products are approved for chickens (broilers only) and/or turkeys.
There are some products containing amprolium alone for use in laying hens.
Human-Approved Products: None