Doses - TESTOSTERONE CYPIONATE, TESTOSTERONE ENANTHATE, TESTOSTERONE PROPRIONATE

Dogs:

For testosterone-responsive urinary incontinence (may be used with phenylpropanolamine):
a) Testosterone propionate: approximately 2 mg/kg IM or SQ 3 times per week.
Testosterone cypionate: 200 mg IM once per month. (LaBato 1988), (Polzin and Osborne 1985)
b) Testosterone propionate: 2.2 mg/kg IM q2-3 days.
Testosterone cypionate: 2.2 mg/kg IM once per month. (Moreau and Lappin 1989), (Chew, DiBartola, and Fenner 1986)

Cats:

For testosterone-responsive urinary incontinence (may be used with phenylpropanolamine):
a) Testosterone propionate 5 - 10 mg IM (Barsanti and Finco 1986)

Cattle:

To produce an estrus-detector (teaser) animal (cull cows, heifers, steers):
a) Testosterone propionate 200 mg IM on day 1 and on days 4-9. On day 10, give 1 gram IM and attach a chinball marker and put with the breeding herd. To maintain the teasergive 1 gram booster every 10-14 days.
Alternatively, initially give testosterone enanthate 0.5 gram IM and 1.5 gram SQ(divided in two separate locations). After 4 days attach chinball marker and put in withbreeding herd. To maintain, give 0.5 - 0.75 gram SQ every 10-14 days. (Wolfe 1986)
Monitoring Parameters -

1) Efficacy

2) Adverse effects
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products: No known testosterone products (with the exception ofcombinations with estradiol as growth promotant implants) approved for use in veterinary specieswere located. Testosterone propionate (200 mg) is also available in combination with estradiolbenzoate (20 mg) as a growth promotant in beef cattle. Trade names include HEIFER-oid® (Bio-Ceutic) and Synovex-H® (Syntex); (Rx)

Human-Approved Products:

Testosterone Cypionate (in oil) for injection 50 mg/ml, 100 mg/ml, & 200 mg/ml in 1 & 10 mlvials. Available generically and in many proprietary labeled products. A commonly knowntrade name is Depo-Testosterone® (Upjohn); (Rx).
Testosterone Enanthate (in oil) for injection 100 mg/ml and 200 mg/ml in 5 and 10 ml vials & 1ml syringes; Available generically and in many proprietary labeled products; (Rx)
Testosterone Propionate Injection (in oil): 100 mg/ml in 10 ml vials 25 mg/ml, 50 mg/ml, & 100mg/ml in 10 ml and 30 ml vials; Available generically; (Rx)
Testosterone products are now controlled substances (C-III).