Veterinary Drug Handbook (VDH) is the reference veterinarians turn to when they want an independent source of information on the drugs that are used in veterinary medicine today.

Doses - TILETAMINE HCL / ZOLAZEPAM HCL, (Telazol®)

Dogs: Dog

a) For diagnostic purposes: 6.6 - 9.9 mg/kg IM
For minor procedures of short duration: 9.9 - 13.2 mg/kg IM
If supplemental doses are necessary, give doses less than the initial dose and total dosage should not exceed 26.4 mg/kg. Atropine 0.04 mg/kg should be used concurrently to control hypersalivation. (Package Insert; Telazol® - Robins)
b) For surgical interventions of 30-60 minutes: 6 - 13 mg/kg IM (Booth 1988a)

Cats: Cat

a) 9.7 - 11.9 mg/kg IM for procedures such as dentistry, abscess treatment, foreign body removal, etc. For procedures that require mild to moderate levels of analgesia (lacerations, castration, etc.) use 10.6 - 12.5 mg/kg IM.
For ovariohysterectomy and onychectomy use 14.3 - 15.8 mg/kg IM.
If supplemental doses are necessary, give doses less than the initial dose and the total dosage should not exceed 72 mg/kg. Atropine 0.04 mg/kg should be used concurrently to control hypersalivation. (Package Insert; Telazol® - Robins)
b) For surgical interventions of 30-60 minutes: 6 - 13 mg/kg IM (Booth 1988a)
Pocket Pets:
Gerbils: 20 mg/kg IP (in combination with xylazine 10 mg/kg) (Huerkamp 1995)

Horses: Horse

a) Xylazine 1.1 mg/kg IV, 5 minutes prior to Telazol® at 1.65 - 2.2 mg/kg IV (Hubbell,
Bednarski, and Muir 1989)
Exotic Species:
a) An extensive list of suggested Telazol® dosages may be found in the article by E.
Schobert entitled, "Telazol® Use in Wild and Exotic Animals" in the October 1987issue of Veterinary Medicine.
Monitoring Parameters -
  • 1) Level of anesthesia/analgesia
  • 2) Respiratory function; cardiovascular status (rate, rhythm, BP if possible)
  • 3) Monitor eyes to prevent drying or injury
  • 4) Body temperature
    Client Information - Should only be administered by individuals familiar with its use.
    Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products:
    Tiletamine HCl (equivalent to 250 mg free base) & Zolazepam HCl (equivalent to 250 mg free base) as lyophilized powder/vial in 5 ml vials. When 5 ml of sterile diluent (sterile water) is added a concentration of 50 mg/ml of each drug (100 mg/ml combined) is produced.; Telazol® (Fort Dodge); (Rx) Approved for use in cats and dogs. Telazol® is a Class III controlled substance.
    Human-Approved Products: None
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