Doses - ATENOLOL

Dogs:

For indications where beta blockade may be indicated (cardiac arrhythmias, obstructive heartdisease, hypertension, myocardial infarction, etc.):
a) 12.5 - 50 mg once or twice daily. Start at a low dose and titrate upwards as necessary. (Ware 1992)
b) 0.25 - 1 mg/kg PO q12-24h (Miller, Tilley et al. 1994)
c) 6.25 - 25 mg (total dose) q12h (Muir and Bonagura 1994)
For treatment of hypertension:
a) 2 mg/kg once daily (Littman 1992)

Cats:

For treatment of hypertension:
a) 2 mg/kg once daily; hyperthyroid cats being started on methimazole are treated usuallyfor 2 weeks with atenolol. It is important to closely monitor geriatric cats as renaldisease may be a concurrent problem with hyperthyroidism or hypertension. (Littman 1992)
For indications where beta blockade may be indicated (cardiac arrhythmias, obstructive heartdisease, hypertension, myocardial infarction, etc.):
a) 6.25 - 12.5 mg total dose PO once daily (q24h) (Miller, Tilley et al. 1994), (Muir and Bonagura 1994)
Monitoring Parameters -
1) Cardiac function, pulse rate, ECG if necessary, BP if indicated; 2) Toxicity (see Adverse
Effects/Overdosage)
Client Information - To be effective, the animal must receive all doses as prescribed. Notifyveterinarian if animal becomes lethargic or becomes exercise intolerant, develops shortness ofbreath or cough, or develops a change in behavior or attitude. Do not stop therapy without firstconferring with veterinarian.
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products: None

Human-Approved Products:

Atenolol Tablets 25, 50, & 100 mg; Tenormin® (ICI), Generic; (Rx)Atenolol Injection 5 mg/ml in 10 ml amps; Tenormin® (ICI); (Rx)
Also available in an oral fixed dose combination product with chlorthalidone.