Veterinary Drug Handbook (VDH) is the reference veterinarians turn to when they want an independent source of information on the drugs that are used in veterinary medicine today.

SMZ-Med 454

Product Type: OTC ANIMAL DRUG LABEL
Autor Name: Bimeda, Inc. Division of Cross Vetpharm Group Ltd.
Code Source: 61133-8001
Route of Administration: ORAL

SMZ-Med 454

Generic: Sodium Sulfamethazine

Ingredients:

  • Sulfamethazine Sodium Cation : Active ingredient - basis of strength - 453.5 g in 453.5 g

Package Description:

  • 453.5 g in 1 POUCH
INDICATIONS:
For the control and treatment of the following diseases when caused by one or more of the following pathogenic organisms susceptible to sulfamethazine.
FOR THE TREATMENT OF:
CATTLE - Bacterial Pneumonia and Bovine Respiratory Disease Complex (Shipping Fever Complex) ( Pasteurella spp.); Colibacillosis (Bacterial Scours) ( Escherichia coli ); Necrotic Pododermatitis (Foot Rot)( Fusobacterium necrophorum ); Calf Diptheria ( Fusobacterium necrophorum ); Acute Metritis ( Streptococcus spp.)
BEEF CATTLE - Acute Mastitis ( Streptococcus spp.)
SWINE - Porcine Colibacillosis (Bacterial Scours) ( Escherichia coli ); Bacterial Pneumonia ( Pasteurella spp.)
FOR CONTROL OF:
CHICKENS - Infectious Coryza ( Haemophilus gallinarum ); Coccidiosis ( Eimeria tenella, Eimeria necatrix ); Acute Fowl Cholera ( Pasteurella multocida ); Pullorum Disease ( Salmonella pullorum )
TURKEYS - Coccidiosis ( Eimeria meleagrimitis, Eimeria adenoeides )

ADMINISTRATION IN DRINKING WATER
Prepare a 12.0% stock solution by adding the contents of this package to one gallon of water.
DOSAGE: CATTLE, CALVES AND SWINE
1st day: 6 tablespoons (3 fl oz) for each 100 lb body weight, providing approximately 108 mg/lb (237.6 mg/kg) body weight.
2nd, 3rd, 4th days: 3 tablespoons (1 1/2 fl oz) for each 100 lb body weight, providing approximately 54 mg/lb (118.8 mg/kg) body weight.
DOSAGE: POULTRY: Add 2 tablespoons (1 fl oz) to each gallon, or one gallon of stock solution to 128 gallons. Following administration directions, this will provide a recommended dose of approximately 58 to 85 mg/lb/day (128 to 187 mg/kg/day) body weight in chickens and 50 to 124 mg/lb/day (110 to 273 mg/kg/day) body weight in turkeys, depending upon the dosage, age, class of chickens or turkeys, ambient temperature and other factors.

RESIDUE WARNINGS: Do not medicate chickens or turkeys producing eggs for human consumption. To avoid drug residues in edible flesh withdraw medication from chickens and turkeys ten (10) days prior to slaughter for food.
Treated cattle must not be slaughtered for at least ten (10) days after the last dose. Exceeding five (5) consecutive days of treatment may cause violative tissue residue to remain beyond the withdrawal time. Do not use in calves under one (1) month of age or calves being fed an all-milk diet. Use in these classes of calves may cause violative residues to remain beyond the withdrawal time. Do not use in female dairy cattle 20 months of age or older. Use of sulfamethazine in this class of cattle may cause milk residues.
CAUTION: For best advice in control and treatment of animal disease, consult a veterinarian. Have only medicated water available during treatment, and check carefully to insure adequate drug dosage and water intake. Cattle and calves not drinking or eating must be dosed by drench or with immediate release sulfamethazine bolus. For best results, treat sick animals individually. In poultry, consult a veterinarian or poultry pathologist for diagnosis. For control of outbreaks of disease, medication should be initiated as soon as the diagnosis is determined. Medicated cattle, swine, chickens and turkeys must actually consume enough medicated water which provides the recommended dosages. SMZ-Med 454 works fast. If symptoms persist after using this preparation for 2 or 3 days, consult a veterinarian. Excessive dosage may cause toxic reactions. Follow dosage and administration instructions carefully. Hatchability of eggs laid during medication of sulfas, and for short periods thereafter, may be adversely affected. Treatment of all diseases should be instituted early. Treatment should continue 24 to 48 hours beyond the remission of disease symptoms, but not to exceed a total of 5 consecutive days in cattle or swine.

ADMINISTRATION:
CATTLE, CALVES AND SWINE:
In Drinking Water: Add the required dose given above to that amount of water that will be consumed in one day; consumption should be carefully checked. Factors such as temperature, humidity and disease will cause variable fluid intake. As a generalization, the above animals will consume approximately 1 gallon per 100 lb body weight per day.
As a Drench: Dilute the proper dose of stock solution, and drench or administer with dose syringe. Cattle and calves not drinnking must be dosed by drench or with immediate release sulfamethazine bolus. For best results, pen-up animals to be treated, and treat sick animals individually.
CHICKENS AND TURKEYS:
Add the required dose to that amount of water that will be consumed in one day. water consumption should be carefully checked to insure adequate drug intake. As a generalization, 100 turkeys will drink one gallon of water per day for each week of age; chickens will consume one-half this amount.
INFECTIOUS CORYZA (in chickens): Medicate for 2 consecutive days.
ACUTE FOWL CHOLERA AND PULLORUM DISEASE (in chickens): Medicate for 6 consecutive days.
COCCIDIOSIS (in chickens and turkeys): Medicate as above for 2 days, then reduce drug concentration to one-half above for 4 additional days.

SMZ-Med 454
Sodium Sulfamethazine
Soluble Powder
Antibacterial
FOR ANIMAL USE ONLY
KEEP OUT OF REACH OF CHILDREN
CONVENIENT, ONCE-A-DAY DOSAGE IN DRINKING WATER OR AS A DRENCH
Prepare Fresh Solutions Daily
Contents 100% sodium sulfamethazine
Store at controlled room temperature 20 o - 25 o C (68 o - 77 o F), with excursions permitted to 15 o - 30 o C (59 o - 86 o F).
Restricted Drug (California) - Use Only as Directed
ANADA 200-434 Approved by FDA
Net Wt. 453.5 g (1 lb.)

SMZ Med 454 453.5g pouch
SMZ-Med 454


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