Doses - ATRACURIUM BESYLATE

Dogs:

a) Induction dose: 0.22 mg/kg IV, give 1/10th to 1/6th of this dose initially as a "priming"dose, followed 4-6 minutes later with the remainder and a sedative/hypnotic agent.
Intraoperative dose: 0.11 mg/kg IV (Mandsager 1988)
b) After acepromazine and/or meperidine premedication, give 0.5 mg/kg IV initially. Induceanesthesia with thiopental or methohexital; after intratracheal intubation maintainanesthesia with nitrous oxide:oxygen (2:1) and halothane (0.5%), using controlledventilation. Additional doses of atracurium may be administered at 0.2 mg/kg IV. (Jones 1985b)

Cats:

a) Induction dose: 0.22 mg/kg IV, give 1/10th to 1/6th of this dose initially as a "priming"dose, followed 4-6 minutes later with the remainder and a sedative/hypnotic agent.
Intraoperative dose: 0.11 mg/kg IV (Mandsager 1988)

Horses:

a) Intraoperative dose: 0.055 mg/kg IV (Mandsager 1988)
Monitoring Parameters -
1) Level of neuromuscular blockade; cardiac rate
Client Information - This drug should only be used by professionals familiar with its use.
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products: None

Human-Approved Products:

Atracurium Besylate Injection 10 mg/ml in 5 ml amps and 10 ml vials; Tracrium® (Glaxo
Wellcome); (Rx)