Doses - CLONAZEPAM
Dogs:
As an adjunctive medication in the treatment of seizures: a) 0.5 mg/kg PO q8-12h (Papich 1992)
b) 0.5 mg/kg q12h (Fenner 1994)
c) 0.5 mg/kg PO bid-tid; may need to lower phenobarbital dose by 10-20%. (Neer 1994)
Monitoring Parameters - 1) Efficacy; 2) Adverse Effects. The therapeutic blood level has beenreported as 0.015 - 0.07 micrograms/ml.
Client Information - A major factor in anticonvulsant therapy failure is lack of compliance withthe prescribed therapy. Owners must be counseled on the importance of giving doses regularly.
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products: None
Human-Approved Products:
Clonazepam Oral Tablets 0.5 mg, 1 mg, 2 mg; Klonopin® (Roche) (Rx);Clonazepam®(Lemmon) (Rx)All clonazepam products are controlled drugs (C-IV).