Veterinary Drug Handbook (VDH) is the reference veterinarians turn to when they want an independent source of information on the drugs that are used in veterinary medicine today.

Doses - DACTINOMYCIN

Also see the section on antineoplastic protocols found in the appendix.
a) 0.7 mg/m2 IV every 7 days (Jacobs, Lumsden et al. 1992)
Monitoring Parameters - 1) Efficacy; 2) Toxicity: including CBC with differential and platelets;hepatic function tests; check inside patient's mouth for ulceration
Client Information - Inform clients of the potential toxicities and risks associated with this therapy and to report immediately any signs associated with serious toxicity (e.g., bloody vomiting or diarrhea, abnormal bleeding, bruising, urination, depression, infection, shortness of breath, etc.).
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products: None

Human-Approved Products:

Dactinomycin for Injection 500 micrograms (with 20 mg mannitol); Cosmogen® (MSD); (Rx)
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