Doses - DICHLORPHENAMIDE

Dogs:

a) 2 - 5 mg/kg PO q8h (Davis 1985)
b) 10 - 15 mg/kg per day divided 2-3 times daily (Brooks 1986)
c) 2 - 5 mg/kg PO divided tid (Wyman 1986)
d) 2 - 4 mg/kg PO bid-tid (Morgan 1988)

Cats:

a) 10 - 25 mg (total) q8h PO (Davis 1985)
b) 1 mg/kg PO bid-tid (Morgan 1988)
Monitoring Parameters -

1) Intraocular pressure/tonometry

2) Serum electrolytes

3) Baseline CBC with differential and periodic retests if using chronically.

4) Other adverse effects
Client Information - If GI upset occurs, give with food. Notify veterinarian if abnormal bleeding or bruising occurs or if animal develops tremors or a rash.
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products: None
Human-Approved Products: At the time this edition went to press, there were rumors that the manufacturer was discontinuing this product and it may not be available.
Dichlorphenamide 50 mg Tablets (scored); Daranide® (Merck); (Rx)