Doses - AMINOCAPROIC ACID

Dogs:

For adjunctive treatment of degenerative myelopathy (seen primarily in German shepherds):
a) In combination with exercise, vitamin support (vitamin B-complex, vitamin E), andanalgesia (if required; using acetaminophen): Aminocaproic acid: 500 mg (regardless ofsize of animal, approximate dose is 15 mg/kg) PO q8h. Mix 192 ml of the 250 mg/mlinjection with 96 ml of hematinic compound (e.g. Lixotinic®) producing a 288 ml finalvolume. Give 3 ml per dose (500 mg). Store solution in refrigerator. Clinicalimprovement seen within 8 weeks. (Clemmons 1991)
Client Information - Drug costs to treat a German shepherd-sized dog can be substantial.
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products: None

Human-Approved Products:

Aminocaproic Acid Tablets 500 mg; Aminocaproic Oral Solution 250 mg/ml; Amicar®(Immunex); (Rx)
Aminocaproic Acid Injection for Intravenous Infusion 250 mg/ml (5 gram); Amicar®
Intravenous (Immunex); Generic; (Rx)