Doses - AMOXICILLIN
Dogs:
For susceptible infections: a) 10 - 22 mg/kg PO or SubQ q8h (Vaden and Papich 1995)
b) Trihydrate injectable (Amoxi-Inject®): 5.5 - 11 mg/kg IM or SQ q8h
Oral Forms: 11 - 22 mg/kg PO q8-12h (Aronson and Aucoin 1989)
c) For routine infections: 10 mg/kg PO, SQ bid
For chlolangiohepatitis: 20 mg/kg PO, SQ bid (Morgan 1988)
d) 22 mg/kg PO q12h (Kirk 1989)
e) 10 - 55 mg/kg q6-12h PO; 5 - 11 mg/kg IV, IM, or SQ q6-12h (Greene 1984)
f) For Lyme Disease: 22 mg/kg PO q12h for 21-28 days (Appel and Jacobson 1995)
Cats:
For susceptible infections: a) 10 - 22 mg/kg PO or SubQ q8h (Vaden and Papich 1995)
b) Trihydrate injectable (Amoxi-Inject®): 5.5 - 11 mg/kg IM or SQ q8h
Oral Forms: 11 - 22 mg/kg PO q8-12h (Aronson and Aucoin 1989)
c) 11 - 22 mg/kg PO q8-12h (Ford and Aronson 1985)
d) For bacterial respiratory infections: 10 mg/kg PO or parenterally q12-24h (Roudebush1985)
e) 22 mg/kg PO q12h (Kirk 1989)
Cattle:
For susceptible infections: a) 6 -10 mg/kg SQ or IM q24h (Withdrawal time = 30 days). (Jenkins 1986)
b) For respiratory infections: 11 mg/kg IM or SQ q12h. (Hjerpe 1986)
c) For respiratory infections: 11 mg/kg IM or SQ q12h (Beech 1987b)
d) Calves: Amoxicillin trihydrate: 7 mg/kg PO q8-12h (Baggot 1983)
e) 13.2 - 15.4 mg/kg IM or SQ once daily (Upson 1988)
Horses:
For susceptible infections: a) For respiratory infections: 20 - 30 mg/kg PO q6h (Beech 1987b)
b) Amoxicillin trihydrate: 20 mg/kg q12h IM. (Upson 1988)
Birds:
For susceptible infections: a) For most species: 150 - 175 mg/kg PO once to twice daily (using 50 mg/ml suspension) (Clubb 1986)
b) 100 mg/kg q8h PO (Bauck and Hoefer 1993)
c) 100mg/kg q8h, IM, SubQ, PO (Hoeffer 1995)
Reptiles:
For susceptible infections: a) For all species: 22 mg/kg PO q12-24h; not very useful unless used in combination withaminoglycosides. (Gauvin 1993)
Client Information - The oral suspension should preferably be refrigerated, but refrigeration isnot absolutely necessary; any unused oral suspension should be discarded after 14 days.
Amoxicillin may be administered orally without regard to feeding status. If the animal developsgastrointestinal symptoms (e.g., vomiting, anorexia), giving with food may be of benefit.
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products:
Amoxicillin Oral Tablets 50 mg, 100 mg, 150 mg, 200 mg, , 400 mg; Amoxi-Tabs® (Pfizer), (Rx) Approved for use in dogs and cats. Robamox-V® (Fort Dodge); (Rx) Approved for usein dogs only.
Amoxicillin Powder for Oral Suspension 50 mg/ml (after reconstitution) in 15 ml or 30 mlbottles; Amoxi-Drop® (Pfizer); (Rx); Approved for use in dogs and cats.Robamox-V® (Fort
Dodge) (Rx); Approved for use in dogs.
Amoxicillin Oral Bolus 400 mg; Amoxi-Bol® (Pfizer); (Rx) Approved for use in non-ruminatingcalves, including veal calves. Slaughter withdrawal = 20 days.
Amoxicillin Powder for Suspension (Injection): 3 gram vial (Dogs, Cats) and 25 g vial (nonlactating cattle); Amoxi-Inject® (Pfizer); (Rx) Approved for use in dogs and cats (3 g vial),
Slaughter withdrawal (cattle) = 25 days. Milk withdrawal = 96 hours.
Amoxicillin Intramammary Infusion 62.5 mg/syringe in 10 ml syringes; Amoxi-Mast® (Pfizer);(Rx) Approved for use in lactating dairy cattle. Slaughter withdrawal = 12 days; Milkwithdrawal = 60 hours.
Human-Approved Products:
Amoxicillin Tablets (chewable) 125 mg (As trihydrate) & 250 mg (as trihydrate);Amoxil ®(SKBeecham); generic, (Rx)
Amoxicillin Capsules (as trihydrate) 250 mg, 500 mg; Polymox® (Apothecon); Wymox®(Wyeth-Ayerst); generic (Rx)
Amoxicillin (as the trihydrate) Powder for Oral Suspension 50 mg/ml (as trihydrate) (in 15 and30 ml bottles), 125 mg/5 ml (as trihydrate) and 250 mg/5 ml (as trihydrate) 80 ml, 100 ml, 150ml, and 200 ml bottles. (Rx)