Doses - PRAZIQUANTEL

Dogs:

For susceptible cestodes:
a) IM or SubQ using the 56.8 mg/ml injectable product:
Body weight
Dose5 lbs or less 17 mg (0.3 ml)6-10 lbs28.4 mg (0.5 ml)11-25 lbs56.8 mg (1.0 ml)over 25 lbs.0.2 ml/5 lb body weight - max. of 3 ml
Oral: Using the 34 mg canine tablet:5 lbs or less 17 mg (1/2 tab)6-10 lbs.34 mg (1 tab)11-15 lbs51 mg (1.5 tabs)16-30 lbs68 mg (2 tabs)31-45 lbs102 mg (3 tabs)46-60 lbs136 mg (4 tabs)over 60 lbs.170 mg (5 tabs - max.); (Package insert; Droncit® Injectable &
Tablets¯Miles)
b) 5 mg/kg (Chiapella 1988)
c) For Echinococcus granulosis: 10 mg/kg (Sherding 1989)
d) For Diphyllobothrium sp: 7.5 mg/kg PO once. (Kirkpatrick, Knochenhauer, and Jacobsen 1987)
e) For Spirometra mansonoides or Diphyllobothrium erinacei: 7.5 mg/kg PO once dailyfor 2 days. (Roberson 1988a)
For treatment of Paragonimiasis:
a) 25 mg/kg bid PO for 2 consecutive days. (Kirkpatrick and Shelly 1987)
b) 23 mg/kg PO q8h for 3 days (Reinemeyer 1995)

Cats:

For susceptible cestodes:
a) 5 mg/kg (Chiapella 1988)
b) IM or SubQ using the 56.8 mg/ml injectable product:
Body weight
Dose
Under 5 lbs11.4 mg (0.2 ml)5-10 lbs22.7 mg (0.4 ml)10 lbs and over34.1 mg (0.6 ml - max)
Oral: Using the 23 mg feline tab
Body weight
Dose4 lbs and under11.5 mg (1/2 tab)5-11 lbs23 mg (1 tab)over 11 lbs34.5 mg (1.5 tabs)(Package insert; Droncit® Injectable & Tablets¯Miles)
For treatment of Paragonimiasis:
a) 23 mg/kg PO q8h for 3 days (Reinemeyer 1995)

Sheep & Goats:

For all species of Moniezia, Stilesia, or Avitellina:
a) 10 - 15 mg/kg (Roberson 1988a)
Llamas:
For susceptible parasites:
a) 5 mg/kg PO. (Fowler 1989)

Birds:

For susceptible parasites (tapeworms):
a) 1/4 of one 23 mg tablet/kg PO; repeat in 10-14 days. Add to feed or give by gavage.
Injectable form is toxic to finches. (Clubb 1986)
b) For common tapeworms in chickens: 10 mg/kg. (Roberson 1988a)
c) For cestodes and some trematodes: Direct dose: 5 - 10 mg/kg PO or IM as a singledose -or- 12 mg of crushed tablets baked into a 9"x9"x2" cake. Finches should havetheir regular food withheld and be pre-exposed to a non-medicated cake. (Marshall1993)

Reptiles:

a) For cestodes and some trematodes in most species: 7.5 mg/kg PO once; repeat in 2weeks PO (Gauvin 1993)
b) For removal of common tapeworms in snakes: 3.5 - 7 mg/kg (Roberson 1988a)
Monitoring Parameters -
1) Clinical efficacy
Client Information - Fasting is not required nor is it recommended before dosing. A single doseis usually effective, but measures should be taken to prevent reinfection, particularly against D.caninum. Tablets may be crushed or mixed with food. Because tapeworms are often digested, wormfragments may not be seen in the feces after using.
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products:
Praziquantel 23 mg (feline), 34 mg (canine) Tablets; Droncit® Tablets (Bayer); (Rx) Approvedfor use in cats and dogs.
Praziquantel Injection 56.8 mg/ml in 10 ml vials; Droncit® Injection (Bayer); (Rx) Approvedfor use in cats and dogs.
Praziquantel/pyrantel pamoate; Drontal Tablets® (Bayer) (Rx) Approved for use in catsPraziquantel/pyrantel pamoate plus febantel; Drontal Plus Tablets® (Bayer) (Rx) small, mediumand large dog sizes

Human-Approved Products:

Praziquantel Tablets 600 mg; Biltricide® (Bayer) (Rx)