Veterinary Drug Handbook (VDH) is the reference veterinarians turn to when they want an independent source of information on the drugs that are used in veterinary medicine today.

Oxytocin Injection Purified Oxytocic Principle (20 USP Units per mL) FOR ANIMAL USE ONLY HAZARDOUS KEEP OUT OF REACH OF CHILDREN

Product Type: PRESCRIPTION ANIMAL DRUG LABEL
Autor Name: VetTek
Code Source: 60270-841
Route of Administration: SUBCUTANEOUS

Oxytocin Injection

Generic: Oxytocin

Ingredients:

  • Oxytocin Oxytocin : Active ingredient - basis of strength - 20 [USP'U] in 100 mL

Package Description:

  • 100 mL in 1 VIAL, MULTI-DOSE

Description

Oxytocin Injection is a sterile aqueous solution of highly purified oxytocic principle derived by synthesis or obtained from the posterior lobe of the pituitary gland of healthy domestic animals used for food by humans. Oxytocin injection contains 20 USP Units of oxytocin and less than 0.4 units of presser activity per mL. Each mL of sterile solution also contains 0.9% w/v sodium chloride, 0.5% w/v chlorobutanol (as a preservative), with water for injection q.s. and pH adjusted to 3.0 to 5.0 with acetic acid.

Actions

Oxytocin acts directly on the smooth musculature of the uterus in all species to induce rythmic contractions, although in some species the uterine cervix does not respond to oxytocin. The responsiveness of the uterine musculature to oxytocin varies greatly with the stage of the reproductive cycle. During the early phases of pregnancy the uterus is relatively insensitive to the effects of oxytocin, while in the late phases the sensitivity is markedly increased. Most authorities attribute this varying response to the varying levels of estrogen and progesterone during the course of pregnancy. Oxytocin also has been shown to exert a milk ejecting effect, occasionally referred to as the galactogogic effect. The actual mechanism by which oxytocin stimulates the release of milk from the mammary glands is not known with certainty, but oxytocin is presumed to act on certain smooth muscle elements in the gland.

Indications

Because of the specific action of oxytocin upon the uterinne musculature, it is recommended as an aid in the management of the following conditions:
1) To precipitate labor
2) To accelerate normal parturition
3) Postpartum evacuation of uterine debris
4) Postoperative contraction of the uterus following a cesarean section and control of uterine hemorrhage.
Oxytocin will contract the smooth muscle cells of the mammary gland to induce milk let-down if the udder is in a proper physiological state.

Contraindications

Do not use in dystocia due to abnormal presentation of the fetus until correction is accomplished.

Precautions

Oxytocin is a potent preparation, accordingly, it should be administered with due caution. For prepartum usage full dilation of the cervix should be accomplished either naturally or through the administration of estrogen prior to oxytocin therapy.

Dosage and Administration

Obstetrical Use: Inject aseptically by the intravenous, intramuscular or subcutaneous route as follows:
EWES, SOWS:
1.5 to 2.5 mL..30 to 50 USP Units
COWS, HORSES:
5.0 mL...........100 USP Units
These dosages are recommended, and may be repeated as indicated.
Milk Let-down:
Inject aseptically by the intravenous, intramuscular or subcutaneous route.
COWS:
0.5 to 1.0 mL.....10 to 20 USP Units
SOWS:
0.25 to 1.0 mL....5 to 20 USP Units
These dosages are recommended and may be repeated as necessary.
Note: Oxytocin will not induce milk let-down unless the udder is in the proper physiological state.

Caution

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

100 mL multiple dose vials.

Storage

Store at controlled room temperature.
Do Not Freeze.


Package Label Display Panel

NDC 60270-841-10
Oxytocin
Injection
Purified Oxytocic Principle
Sterile Aqueous Solution
CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.
FOR ANIMAL USE ONLY
KEEP OUT OF REACH OF CHILDREN
ANADA# 200-328, Approved by FDA
Net Contents: 100 mL (3.4 fl. oz)

image of 100 mL bottle
Oxytocin Injection Purified Oxytocic Principle (20 USP Units per mL) FOR ANIMAL USE ONLY HAZARDOUS KEEP OUT OF REACH OF CHILDREN

© 2011-2021 veterinary-help.com Veterinary Terms, Diagnoses and Drug Handbook Online

×
Wait 20 seconds...!!!