Veterinary Drug Handbook (VDH) is the reference veterinarians turn to when they want an independent source of information on the drugs that are used in veterinary medicine today.

Doses - FENTANYL CITRATE / DROPERIDOL

Caution: Doses are for the veterinary product (Innovar-Vet®) which is 8X more concentratedthan the human labeled product (Innovar®).

Dogs: Dog

To prevent bradycardia and excessive salivation, atropine (0.045 mg/kg SQ) or glycopyrrolate should generally be given 15 minutes prior to IV administration or concurrently with IMdose. a) For analgesia and tranquilization: 1 ml per 6.8 - 9.1 kg (0.11 - 0.15 ml/kg) IM or 1 mlper 11.35 - 27 kg (0.037 - 0.088 ml/kg) IV (Package Insert: Innovar®-Vet¯P/M;
Mallinckrodt)
b) For general anesthesia: 1 ml per 18.2 kg (40 lbs.) IM; or 1 ml per 11.35 - 27.3 kg (25 - 60 lbs) IV. Followed by a general anesthetic (barbiturate, halothane, etc.) in 10 minutesafter IM injection and 1 minute after IV injection. (Package Insert; Innovar®-Vet¯P/M;
Mallinckrodt)
c) For tranquilization: 0.3 - 0.5 ml per 55 kg IV
As a preanesthetic: 1 ml per 20 kg IM
As an anesthetic for gastric dilatation: 1 ml per 10 - 30 kg.; dilute in 20 ml of saline, give IV slowly (Morgan 1988)

Cats: Cat

a) 1 ml/9 kg body weight (Innovar®-Vet) SQ; maximal effects occur between 30-60 minutes (Grandy and Heath 1987)
Monitoring Parameters -
  • 1) Level of neuroleptanalgesia
  • 2) Respiratory/cardiovascular status
    Client Information - This drug should only be used by professionals familiar with its effects in a setting where adequate respiratory support can be performed.
    Dosage Forms/Preparations/FDA Approval Status/Withholding Times -
    Note: The veterinary approved product (Innovar®-Vet ) is 8 times more concentrated than the human approved product. Do not confuse the two.
    Veterinary-Approved Products: Note; this product may no longer be marketed.
    Fentanyl citrate 0.4 mg/ml and Droperidol 20 mg/ml for Injection in 20 ml vials
    Innovar®-Vet (Schering Plough); (Rx) Approved for use in dogs.

    Human-Approved Products:

    0.05 mg fentanyl (as citrate) and 2.5 mg droperidol per ml in 2 & 5 ml amps; Innovar® (Janssen); (Rx);Fentanyl Citrate and Droperidol® (Astra) (Rx)
    Innovar® and Innovar®-Vet are Class-II controlled substances.
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