Doses - FIPRONIL
Note: Refer to the package information for specific instructions on application of fipronilproducts.Dogs:
For areas where high risk of infestation, if dog allergic to fleas or where tick control isneeded: Apply Frontline® Top Spot once a month.
For areas with less severe flea infestations, animals without flea dermatitis and where ticksare not a threat: Apply Frontline® Top Spot once every 2-3 months. (Label
Information¯Frontline® Top Spot; Merial)Spray: Intervals as above. 1.5 -3 ml per lbof body weight (1-2 pumps/lb. using the 250 ml btl. and 3-6 pumps/lb. using the 100ml btl.). Pets with long or dense hair coats receive the higher dose rate.
Cats: For flea and tick control: Apply Frontline® Top Spot once a month. (Label
Information¯Frontline® Top Spot; Merial)
Spray: Intervals as above. 1.5 -3 ml per lb of body weight (1-2 pumps/lb. using the 250 mlbtl. and 3-6 pumps/lb. using the 100 ml btl.). Pets with long or dense hair coats receivethe higher dose rate.
Monitoring Parameters - Efficacy
Client Information - Keep product away from children. Do not contaminate food, water or feedand dispose of container properly. Avoid human contact and wear latex gloves when applying/spraying. Avoid contact with animal until dry.
Remains effective after bathing (but do not shampoo within 48 hours of application), water immersion or exposure to sunlight. Spotted areas may appear wet or oily for up to 24 hours after application. Do not reapply for 30 days.
Dosage Forms/Preparations/EPA Approval Status - Veterinary-Approved Products:
Fipronil Topical Solution 9.7% available in cards of 3 pipettes in 0.5 ml (cats/kittens; green), 0.67 ml (dogs up to 22 lb.; gold), 1.34 ml (dogs 23 - 44lbs; blue), 2.68 ml (dogs 45-88 lb.; purple); Frontline® Top Spot (Merial); (OTC) Approved for use in dogs and cats.
Fipronil Topical Spray 0.29% available in 100 ml (cat/small dog¯each spray delivers 0.5 ml) and 250 ml (large dog¯each trigger spray delivers 1.5 ml) spray btls; Frontline® Spray
Treatment (Merial); (OTC) Approved for use in dogs and cats.
Dogs: 
For areas where high risk of infestation, if dog allergic to fleas or where tick control isneeded: Apply Frontline® Top Spot once a month. For areas with less severe flea infestations, animals without flea dermatitis and where ticksare not a threat: Apply Frontline® Top Spot once every 2-3 months. (Label
Information¯Frontline® Top Spot; Merial)Spray: Intervals as above. 1.5 -3 ml per lbof body weight (1-2 pumps/lb. using the 250 ml btl. and 3-6 pumps/lb. using the 100ml btl.). Pets with long or dense hair coats receive the higher dose rate.
Cats: For flea and tick control: Apply Frontline® Top Spot once a month. (Label
Information¯Frontline® Top Spot; Merial)
Spray: Intervals as above. 1.5 -3 ml per lb of body weight (1-2 pumps/lb. using the 250 mlbtl. and 3-6 pumps/lb. using the 100 ml btl.). Pets with long or dense hair coats receivethe higher dose rate.
Monitoring Parameters - Efficacy
Client Information - Keep product away from children. Do not contaminate food, water or feedand dispose of container properly. Avoid human contact and wear latex gloves when applying/spraying. Avoid contact with animal until dry.
Remains effective after bathing (but do not shampoo within 48 hours of application), water immersion or exposure to sunlight. Spotted areas may appear wet or oily for up to 24 hours after application. Do not reapply for 30 days.
Dosage Forms/Preparations/EPA Approval Status - Veterinary-Approved Products:
Fipronil Topical Solution 9.7% available in cards of 3 pipettes in 0.5 ml (cats/kittens; green), 0.67 ml (dogs up to 22 lb.; gold), 1.34 ml (dogs 23 - 44lbs; blue), 2.68 ml (dogs 45-88 lb.; purple); Frontline® Top Spot (Merial); (OTC) Approved for use in dogs and cats.
Fipronil Topical Spray 0.29% available in 100 ml (cat/small dog¯each spray delivers 0.5 ml) and 250 ml (large dog¯each trigger spray delivers 1.5 ml) spray btls; Frontline® Spray
Treatment (Merial); (OTC) Approved for use in dogs and cats.