Veterinary Drug Handbook (VDH) is the reference veterinarians turn to when they want an independent source of information on the drugs that are used in veterinary medicine today.

Doses - PYRANTEL PAMOATE, PYRANTEL TARTRATE

All doses are for pyrantel pamoate unless otherwise noted. Caution: Listed dosages are often notspecified as to whether using the salt or base.

Dogs: Dog

For susceptible parasites:
a) 5 mg/kg PO, repeat in 3 weeks. (Kirk 1989)
b) 15 mg/kg PO 30 minutes after a light meal. Re-treatment recommendations: For hooks:2 weeks; every other week for 5-6 weeks (beginning at 1 week old) if bitch previouslylost pups due to hookworm anemia. For Ascarids: Every other week for 3-4 treatmentsbeginning at 2 weeks old if pups have heavy infestation; retreatment usually notnecessary for mature animals. (Cornelius and Roberson 1986)
c) 5 mg/kg PO; stir liquid before using. (Chiapella 1988)
d) For dogs weighing less than 5 lbs: 10 mg/kg (as base) PO; For dogs weighing morethan 5 lbs: 5 mg/kg (as base) PO. Treat puppies at 2, 3, 4, 6, 8, and 10 weeks of age.
Treat lactating bitches 2-3 weeks after whelping. Do follow-up fecal 2-4 weeks aftertreating to determine need for retreatment. (Label directions; Nemex® Tabs¯Pfizer)

Cats: Cat

For susceptible parasites:
a) Ascarids, Hookworms, Physaloptera: 5 mg/kg PO; repeat in 2 weeks (one time only for
Physaloptera). (Dimski 1989)
b) 10 mg/kg PO, repeat in 3 weeks. (Kirk 1989)

Horses: Horse

For susceptible parasites:
a) 6.6 mg (as base)/kg PO; 13.2 mg (as base)/kg for cestodes. (Robinson 1987), (Roberson 1988b)
b) 19 mg/kg PO (Brander, Pugh, and Bywater 1982)
c) Pyrantel tartrate: 12.5 mg/kg PO (Roberson 1988b)

Swine: Swine

For susceptible parasites:
a) To remove Ascaris suum or Oesophagostomum spp.: Pyrantel tartrate: 22 mg/kg PO(or in feed at a rate of 800 g/ton) as a single treatment. For Ascaris suum only: in feedat a rate of 96 g/ton (2.6 mg/kg) for 3 days. (Paul 1986), (Label instructions from several pyrantel tartrate premix products)
b) Pyrantel tartrate: 22 mg/kg PO; maximum of 2 grams per animal (Roberson 1988b)
c) For ascarids and nodular worms in potbellied pigs: 6.6 mg/kg PO (Braun 1995)

Cattle & Sheep & Goats:Sheep

For susceptible parasites:
a) Pyrantel tartrate: 25 mg/kg PO. (Roberson 1988b) Llamas:
For susceptible parasites:
a) 18 mg/kg PO for one day. (Cheney and Allen 1989), (Fowler 1989)

Birds: Bird

For intestinal nematodes:
a) 4.5 mg/kg PO once. Repeat in 14 days. Suspension is non-toxic and palatable. (Clubb 1986)
b) For nematodes: 100 mg/kg PO as a single dose in psittacines and passerines. (Marshall 1993)
Client Information - Shake suspensions well before administering
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products:
Pyrantel Pamoate Tablets 22.7 mg (of base), 113.5 mg (of base); Nemex® Tabs (Pfizer); (OTC)
Approved for use in dogs.
Pyrantel Pamoate Oral Suspension; 2.27 mg/ml (as base)(for dogs only), 4.54 mg/ml (of base);
Nemex®-2 (Pfizer); RFD Liquid Wormer® (Pfizer) (OTC) Approved for use in dogs & cats.
Pyrantel Pamoate Oral Suspension 50 mg/ml (of base); Strongid® T (Pfizer); (OTC) Approved for use in horses not intended for food.
Pyrantel Pamoate Oral Paste 43.9% w/w pyrantel base in 23.6 g (20 ml) paste (180 mg pyrantel base/ml); Strongid® Paste (Pfizer); (OTC) Approved for use in horses not intended for food.

Human-Approved Products:

Pyrantel Pamoate Oral Suspension or liquid 50 mg/ml (base) in 30 & 60 ml; Antiminth®(Pfizer) (OTC); Reese's Pinworm® (Reese) (OTC); Pin-Rid® (Apothecary) (OTC);Pin-X®(Effcon) (OTC)
Pyrantel Capsules 180 mg (equivalent to 62.5 mg pyrantel base); Pin-Rid® (Apothecary) (OTC);
Reese's Pinworm® (Reese) (OTC)
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