Doses - BETHANECHOL CHLORIDE

Dogs:

For urinary indications:
a) 2.5 - 10 mg SQ q8h; or 5 - 25 mg q8h PO (Polzin and Osborne 1985), (Labato 1988)
b) 5 - 15 mg PO tid; often used with phenoxybenzamine (Chew, DiBartola, and Fenner 1986)
For increased esophageal sphincter tone: 0.5 - 1.0 mg/kg PO q8h (Jones 1985)

Cats:

For urinary indications:
a) 2.5 - 5 mg q8-12h PO (Polzin and Osborne 1985), (Labato 1988)
b) 1.25 - 5 mg PO tid; often used with phenoxybenzamine (Chew, DiBartola, and Fenner1986)

Horses:

a) 0.05 mg/kg SQ; 0.11 - 0.22 mg/kg IV; Start at lower dose first and use cautiously(McConnell and Hughey 1987)

Reptiles:

a) 2.5 mg/kg SQ (McConnell and Hughey 1987)
Monitoring Parameters - Clinical efficacy; urination frequency, amount voided, bladder palpation;
Adverse effects (see above section)
Client Information - Give medication on an empty stomach unless otherwise instructed by veterinarian. Contact veterinarian if salivation or GI (vomiting, diarrhea, or anorexia) effects arepronounced or persist.
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products: None

Human-Approved Products:

Bethanechol Chloride Tablets 5 mg, 10 mg, 25 mg, 50 mg; Urecholine® (Merck, Frosst);
Duvoid® (Roberts); Myotonachol® (Glenwood); PMS-Bethanechol Chloride® (Glenwood);
Generic; (Rx)
Bethanechol Chloride for Injection 5 mg/ml in 1 ml vials and amps; Urecholine® (Frosst); (Rx)
Bicarbonate ¯ see Sodium Bicarbonate