Doses - DOXAPRAM HCL

Dogs & Cats:

a) 1 - 5 mg/kg IV; may repeat prn. To stimulate respirations in newborns: 1- 2 drops undertongue or 0.1 ml IV in umbilical vein (should be used with caution if product containsbenzyl alcohol as a preservative). (Package Insert; Dopram®-V - Robins)
b) Cats: 5 - 10 mg/kg IV (Boothe 1990)

Rabbits & Rodents:

For respiratory depression:
a) Rabbits: 2 - 5 mg/kg SubQ or IV q15 minutes
Rodents: 2 - 5 mg/kg SubQ q15 minutes (Huerkamp 1995)

Cattle & Swine:

a) 5 - 10 mg/kg IV (Howard 1986)

Horses:

a) 0.5 - 1 mg/kg IV at 5 minute intervals (do not exceed 2 mg/kg in foals); For foal resuscitation: 0.02 - 0.05 mg/kg/min IV (Robinson 1987)
Monitoring Parameters -

1) Respiratory rate

2) Cardiac rate and rhythm

3) Blood gases if available and indicated

4) CNS level of excitation

5) Blood pressure if possible and indicated
Client Information- This agent should be used in an inpatient setting or with direct professional supervision.
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products:
Doxapram HCl for Injection: 20 mg/ml; 20 ml multi-dose vial; Dopram-V® (Fort Dodge); (Rx)
Approved for use in dogs, cats & horses
Human-Approved Products:-
Doxapram HCl for Injection: 20 mg/ml in 20 ml vial; Dopram® (Robins); (Rx) ; generic, (Rx)