Doses - AMINOPROPAZINE FUMARATE

The parenteral preparation should be given slowly IV or IM into a large muscle mass.

Dogs:

a) 2.2 - 4.4 mg/kg IM or IV; or 1 - 2 tablets (25 mg tablets) per 25 lbs of body weightq12h. (Package insert; Jenotone® ¯ Coopers)
b) For urge incontinence: 2 mg/kg PO bid (Chew, DiBartola, and Fenner 1986)

Cats:

a) 2.2 - 4.4 mg/kg IM or IV; or 1/4 - 1/2 tablet (25 mg tablets) per 6 lbs of body weightq12h. (Package insert; Jenotone® ¯ Coopers)
b) For urge incontinence: 2 mg/kg PO bid (Chew, DiBartola, and Fenner 1986)

Horses:

a) 0.55 mg/kg (1 ml/100 lbs body weight) IM or IV q12h (Package insert; Jenotone® - Coopers)
Monitoring Parameters - Dependent on reason for use; monitor for efficacy.
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products:
Aminopropazine Fumarate for Injection 25 mg/ml, (as base) 50 ml vials; Jenotone® (Schering-Plough); (Rx)
Aminopropazine Fumarate Tablets 25 mg, bottles of 100; Jenotone® (Schering-Plough); (Rx)
Human-Approved Products: None
Aminopropazine Fumarate may also be known as proquamezine fumarate, tetrameprozine fumarate, or Myspamol® (May & Baker, U.K.).