Veterinary Drug Handbook (VDH) is the reference veterinarians turn to when they want an independent source of information on the drugs that are used in veterinary medicine today.

Doses - ETHYLISOBUTRAZINE HCL

Dogs: Dog

a) 4.4 - 11 mg/kg IM or PO, or 2.2 - 4.4 mg/kg IV. Duration and degree of tranquilizationmay be varied between 6-72 hours by adjusting dosage. Young animals may requirelower dosages. When used as a preoperative medication, the general anesthetic dosageshould be reduced and administered carefully to effect. (Package Insert; Diquel®¯
Coopers)
Monitoring Parameters -
  • 1) Cardiac rate/rhythm/blood pressure if indicated and possible to measure
  • 2) Degree of tranquilization
  • 3) Body temperature (especially if ambient temperature is very hot or cold)
    Client Information - Keep tablets stored in tight, child-resistant containers. Do not freeze injectable preparation. See monitoring parameters above. May discolor the urine to a pink or red-brown color; this is not abnormal.
    Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products:
    Ethylisobutrazine HCl Injection 50 mg/ml in 100 ml vials; Diquel® (Schering-Plough); (Rx)
    Approved for use in dogs.
    Ethylisobutrazine HCl tablets (scored) 50 mg in bottles of 50; Diquel® (Schering-Plough); (Rx)
    Approved for use in dogs.
    Human-Approved Products: None
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