Veterinary Drug Handbook (VDH) is the reference veterinarians turn to when they want an independent source of information on the drugs that are used in veterinary medicine today.

Doses - LOMUSTINE (CCNU)

Dogs: Dog

For control of flea populations: Lufenuron 10 mg/kg PO once monthly. See dosage form recommendations below. (Package Insert¯Program®; Novartis)
For control of fleas, heartworm prevention, hookworm, ascarid or whipworms:
Lufenuron/Milbemycin (Sentinel®) at 10 mg/kg lufenuron/0.5 mg/kg milbemycin POonce monthly. See dosage form recommendations below. (Package Insert¯Program®;
Novartis)
Cats:For control of flea populations: Lufenuron 30 mg/kg PO once monthly or 10 mg/kg SubQonce every 6 months. See dosage form recommendations below. (Package
Insert¯Program®; Novartis)
Monitoring Parameters - Efficacy
Client Information - Must be used every 30 days to maximize efficacy. All animals in a household should be treated. If animal vomits within 2 hours after dosing, the drug should be re-dosed. Ifa dose is missed, re-dose and then resume a monthly dosage regimen (dogs receiving thelufenuron/milbemycin product should be tested in 6 months or more for heartworm exposure withan antigen test). Do not split tablets.
Dosage Forms/Preparations/FDA Approval Status - Veterinary-Approved Products:
Lufenuron Oral Tablets in six tablet cards or strips: 45 mg (for dogs up to 10 lb., ¯brown), 90mg (for dogs 11 to 20 lb., ¯red), 204.9 mg (for dogs 21 to 45 lb., ¯yellow), 409.8 mg (fordogs 46 to 90 lb., ¯white); Program® (Novartis) (Rx). Approved for use in dogs.
Lufenuron Oral Suspension in six tube packs: 135 mg (for cats up to 10 lb., ¯orange), 270 mg(for cats 11 to 20 lb., ¯green); Program® (Novartis) (Rx). Approved for use in cats.
Lufenuron 6 Month Injectable for Cats 100 mg/ml in 10 syringe packages: 0.4 ml (40 mg) prefilled syringe (for cats up to 8.8 lb.), 0.8 ml (80 mg) prefilled syringe (for cats 8.9 - 17.6 lb.);
Program® 6 Month Injectable (Novartis) (Rx). Approved for use in cats.
Milbemycin/Lufenuron Oral Tablets in six tablet cards: 2.3 mg/46 mg (for dogs 2 to 10lb., ¯brown), 5.75 mg/115 mg (for dogs 11 to 25 lb., ¯green), 11.5 mg/230 mg (for dogs 26to 50 lb., ¯yellow), 23 mg/460 mg (for dogs 51 to 100 lb., ¯white); Sentinel® Flavor Tabs(Novartis) (Rx). Approved for use in dogs.
Lysodren® - see Mitotane
Magnesium Containing Laxatives - see Saline/Hyperosmotic Laxatives
Magnesium Containing Antacids - see Antacids, Oral
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