Doses - OPIATE ANTIDIARRHEALS, PAREGORIC, DIPHENOXALATE HCL / ATROPINE SULFATE, LOPERAMIDE HCL

Dogs & Cats:

For susceptible infections:
a) 2.5 mg/kg - 7.5 mg/kg once daily PO. Higher end of the dosing range may be necessaryin hospitalized patients, those with underlying disease (e.g., malignancy) or structuralalterations (e.g. burns, complicated urinary tract infections, foreign body infections), infections associated with vascular compromise and infections caused by "problem"pathogens. (Package Insert¯Orbax®)
Monitoring Parameters/Client Information - Efficacy is the most important monitoring parameter; clients should be instructed on the importance of giving the medication as instructed andnot to discontinue it on their own.
Dosage Forms/Preparations/FDA Approval Status - Human-Approved Products: None
Veterinary-Approved Products:
Orbifloxacin Oral Tablets: 5.7 mg (yellow) in btls of 250; 22.7 mg (green; E-Z Break) in btls of250; 68 mg (blue; E-Z Break) in btls of 100; Orbax® (Schering-Plough Animal Health); (Rx).
Approved for use in dogs and cats. Federal law prohibits the use of the drug in food-producing animals.
Ormetoprim - see Sulfadimethoxine/Ormetoprim