Doses - PRAZOSIN HCL

Dogs:

a) For treatment of heart failure, systemic hypertension, or pulmonary hypertension: 1 mgper 15 kgs of body weight PO tid (bid-tid for systemic hypertension) (Morgan 1988)
b) For treatment of heart failure: 1 mg PO tid for dogs weighing less than 15 kg; 2 mg tid
PO for dogs weighing more than 15 kg. (Kittleson 1985b)
c) For canine dilated cardiomyopathy: 1 mg for every 15 kg of body weight PO tid; mustuse with a diuretic. (Ogburn 1988)
Monitoring Parameters -

1) Baseline thoracic radiographs

2) Mucous membrane color; CRT

3) If possible, arterial blood pressure and venous pO2
Client Information - Compliance with directions is necessary to maximize the benefits from thisdrug. If possible, give medication with food. Notify veterinarian if patient's condition deterioratesor if the animal becomes lethargic or depressed.
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products: None

Human-Approved Products:

Prazosin Capsules 1 mg, 2 mg, 5 mg; Minipress® (Pfizer); generic (Rx)