Doses - CLEMASTINE FUMARATE

Horses:

As a bronchodilator:
Initially, 0.8 micrograms/kg (practically: 0.5 ml of the commercially available syrup/100lb. BW) twice daily for 3 days; if no improvement increase to 1.6 micrograms/kg(practically: 1 ml of the commercially available syrup/100 lb. BW) twice daily for 3days; if no improvement increase to 2.4 micrograms/kg (practically: 1.5 ml of thecommercially available syrup/100 lb. BW) twice daily for 3 days; if no improvementincrease to 3.2 micrograms/kg (practically: 2 ml of the commercially available syrup/100lb. BW) twice daily for 3 days; if no improvement discontinue therapy. Recommendedduration of therapy is 30 days; then withdraw therapy and reevaluate. If signs return, reinitiate therapy as above. (Package Insert; Ventipulmin®)
Monitoring Parameters - 1) Clinical efficacy; 2) Adverse effects (primarily cardiac rate)
Client Information - Clients should be instructed on the restricted use requirements of this medication and to keep it secure from children or those who may "abuse" it. The drug may prohibitedfrom use by various equine associations (e.g., racing or show).
Dosage Forms/Preparations/FDA Approval Status - Veterinary-Approved Products:
Clenbuterol HCl Oral Syrup 72.5 mcg/ml in 100 ml and 330 ml bottles; Ventipulmin®
Syrup (Boehringer Ingelheim Vetmedica); (Rx). Approved for use in horses not intended for use as food. Extralabel clenbuterol use is prohibited by federal (USA) law.
Human-Approved Products: None