Doses - FLUCONAZOLE

Dogs:

a) For susceptible fungal infections: 2.5 - 5 mg/kg PO once daily for 8-12 weeks (Forneyand Allen 1992)
Cats: For Cryptococcus, urinary tract or CNS mycoses: 2.5 - 10 mg/kg PO q12h (Wolf 1994)
For cryptococcosis: 50 mg PO twice daily. Treatment should continue for 1 month beyondresolution of clinical signs. (Legendre 1995)

Birds:

As an alternate treatment of aspergillosis:
a) 5 - 10 mg/kg PO once daily for up to 6 weeks, with or after amphotericin B. (Oglesbeeand Bishop 1994a)
Monitoring Parameters - 1) Clinical Efficacy; 2) With long-term therapy, occasional liverfunction tests are recommended
Client Information - Compliance with treatment recommendations must be stressed. Have clientsreport any potential adverse effects. Fluconazole therapy may be prolonged (several weeks tomonths) and an average dosage in a cat (50 mg bid) may cost approximately $18/day.
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products: None

Human-Approved Products:

Fluconazole Oral Tablets 50 mg, 100 mg, 150 mg, 200 mg; Diflucan® (Roerig); (Rx)
Fluconazole Powder for oral suspension: 10 mg/ml (when reconstituted) in 350 mg and 40mg/ml (when reconstituted) in 1400 mg; Diflucan® (Roerig) (Rx)
Fluconazole Injection: 2 mg/ml in 100 or 200 ml bottles or Viaflex Plus (available with sodiumchloride or dextrose diluents); Diflucan® (Roerig) (Rx)