METHIMAZOLE, Doses - METHENAMINE MANDELATE, METHENAMINE HIPPURATE

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METHIMAZOLE

↪ Doses - METHIMAZOLE Chemistry - A thioimidazole-derivative antithyroid drug, methimazole occurs as a white to palebuff crystalline powder, having a faint characteristic odor and a melting point of 144 -147°C. It isfreely soluble (1 gram in 5 ml) in water or alcohol.Storage,... ↪ Read more

Doses - METHENAMINE MANDELATE, METHENAMINE HIPPURATE

↪ Description - METHENAMINE MANDELATE, METHENAMINE HIPPURATE Dogs: a) Methenamine hippurate: 500 mg PO q12h; Methenamine mandelate: 10 - 20 mg/kg POq8-12h (Papich 1992)Cats: a) Methenamine hippurate: 250 mg PO q12h (Papich 1992) Monitoring Parameters - 1) Urine pH; 2) Efficacy Client... ↪ Read more

METHENAMINE MANDELATE, METHENAMINE HIPPURATE

↪ Doses - METHENAMINE MANDELATE, METHENAMINE HIPPURATE Chemistry - Methenamine is chemically unrelated to other anti-infective agents. It is commerciallyavailable in two salts, methenamine mandelate and methenamine hippurate. Methenamine mandelateoccurs as a white, crystalline powder and... ↪ Read more

Doses - MERCAPTOPURINE

↪ Description - MERCAPTOPURINE Dogs: For treatment of immune-mediated diseases or acute lymphocytic and granulocytic leukemias: a) 50 mg/m2 PO once daily (q24h) to effect, then every other day (q48h) or as needed.(Jacobs, Lumsden et al. 1992) Monitoring Parameters - 1) Hemograms (including... ↪ Read more

MERCAPTOPURINE

↪ Doses - MERCAPTOPURINE Chemistry - A purine analog, mercaptopurine occurs as a slightly yellow, crystalline powder. It isinsoluble in water and has a pKa of 7.6. Mercaptopurine may also be known as 6-mercaptopurineor 6-MP.Storage, Stability, Compatibility Mercaptopurine tablets should be... ↪ Read more

Doses - MEPHENYTOIN

↪ Description - MEPHENYTOIN Dogs: a) For adjunctive therapy of refractory seizures (not controlled with Phenobarbital orprimidone and potassium bromide): Initially, 10 mg/kg PO every 8 hours; increasedosage to achieve a nirvanol (active metabolite) blood level of 25 - 40... ↪ Read more

MEPHENYTOIN

↪ Doses - MEPHENYTOIN Chemistry - A hydantoin anticonvulsant, mephenytoin occurs a white, crystalline powder. It is veryslightly soluble in water. Mephenytoin is also known as methoin, methylphenylhydantoin orphenantoin.Storage, Stability, Compatibility Store mephenytoin tablets in... ↪ Read more

Doses - MEPERIDINE HCL

↪ Description - MEPERIDINE HCL Dogs: Analgesic duration in dogs usually lasts 45 minutes to 1 hour. Drug may also be given IV, but SLOWLY. a) Analgesic for acute pancreatitis: 5 - 10 mg/kg IM (Morgan 1988) b) Analgesic for burns: 3 - 5 mg/kg IM prn (Morgan 1988) c) Sedative: 5 - 10 mg/kg... ↪ Read more

MEPERIDINE HCL

↪ Doses - MEPERIDINE HCL Chemistry - A synthetic opiate analgesic, meperidine HCl is a fine, white, crystalline, odorlesspowder that is very soluble in water, sparingly soluble in ether and soluble in alcohol. It has a pKaof 7.7 - 8.15 and a melting range of 186 - 189°. The pH of the... ↪ Read more

Doses - MELPHALAN

Dogs: For adjunctive treatment of ovarian carcinoma, multiply myeloma, lymphoreticular neoplasms, osteosarcoma, and mammary or pulmonary neoplasms: a) 2 - 4 mg/m2 PO every 48 hours (every other day). 1.5 mg/m2 PO every 24 hours (oncedaily) for 7 - 10 days. (Jacobs, Lumsden et al. 1992) For... ↪ Read more

MELPHALAN

↪ Doses - MELPHALAN Chemistry - A nitrogen mustard derivative, melphalan occurs as an off-white to buff-coloredpowder that is practically insoluble in water. Melphalan is also known as L-PAM, L-Phenylalanine Mustard, or L-Sarcolysin.Storage, Stability, Compatibility Store melphalan tablets... ↪ Read more

Doses - MEGESTROL ACETATE

↪ Description - MEGESTROL ACETATE NOTE: Because of the low margin of safety; calculate dosages very carefully. Do not confusemg/lb with mg/kg!Dogs: For treatment of heartworm disease: After diagnosis, determine the class (stage) of the disease. Note: The manufacturer providesworksheets... ↪ Read more