Doses - CAPTOPRIL

Dogs:

a) 1 - 2 mg/kg PO tid (start at 1 mg/kg) (Knowlen and Kittleson 1986)
b) 0.5 - 2.0 mg/kg PO q8-12h (Bonagura and Muir 1986)
c) For canine dilated cardiomyopathy: 0.5 - 2 mg/kg PO bid-tid. Used primarily in dogsrefractory to diuretics, other vasodilators, or positive inotropes. (Ogburn 1988)

Cats:

a) 1/4 to 1/2 12.5 mg tablet PO q8-12h (Bonagura 1989)
Monitoring Parameters -

1) Clinical symptoms of CHF

2) Serum electrolytes, creatinine, BUN, urine protein

3) CBC with diff.; periodic

4) Blood pressure (if treating hypertension or symptoms associated with hypotension arise)
Client Information - Give medication on an empty stomach unless otherwise instructed. Do notabruptly stop or reduce therapy without veterinarian's approval. Contact veterinarian if vomiting ordiarrhea persist or are severe, or if animal's condition deteriorates.
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products: None

Human-Approved Products:

Captopril Tablets 12.5, 25, 50, & 100 mg; Capoten® (Bristol-Myers Squibb); Generic (Rx)