Doses - IMIPRAMINE HCL, IMIPRAMINE PAMOATE

Dogs:

a) For urethral incompetence: 5 - 15 mg PO q12h (Labato 1994)
b) For cataplexy: 0.5 - 1 mg/kg tid PO; titrate dose based on clinical effect. (Fenner 1994)
c) For adjunctive treatment of separation anxiety or other tricyclic antidepressant-responsive behavior disorders: 2.2 - 4.4 mg/kg PO once to twice daily. (Marder 1991)

Cats:

a) For urethral incompetence: 2.5 - 5 mg PO q12h (Labato 1994)
Monitoring Parameters - 1) Efficacy; 2) Adverse Effects
Client Information - All tricyclics should be dispensed in child-resistant packaging and kept wellaway from children or pets. Inform clients that several weeks may be required before efficacy isnoted and to continue dosing as prescribed.
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products: None

Human-Approved Products:

Imipramine HCl Tablets 10 mg, 25 mg, 50 mg; Tofranil® (Geigy), Generic; (Rx)Imipramine HCl Injection 12.5 mg/ml in 2 ml amps; Tofranil® (Geigy); (Rx)Imipramine Pamoate Capsules 75 mg, 100 mg, 125 mg, 150 mg; Tofranil®-PM (Geigy); (Rx)
Innovar-Vet® - see Fentanyl/Droperidol