Veterinary Drug Handbook (VDH) is the reference veterinarians turn to when they want an independent source of information on the drugs that are used in veterinary medicine today.

Doses - ENALAPRIL MALEATE, ENALAPRILAT

Dogs: Dog

a) As a vasodilator in heart failure: 0.5 - 1 mg/kg q12-24h (DeLellis and Kittleson 1992)
b) 0.25 - 0.5 mg/kg PO once to twice a day (Muir and Bonagura 1994)
c) For adjunctive treatment of heart failure: 0.5 mg/kg once daily initially with or without food. If response is inadequate increase to 0.5 mg/kg bid (Package Insert¯Enacard®- Merck)

Cats: Cat

a) As a vasodilator in heart failure: Initially, 0.25 mg/kg q12-24h (DeLellis and Kittleson 1992)
b) 0.25 - 0.5 mg/kg PO once to twice a day (Muir and Bonagura 1994)
Monitoring Parameters - 1) Clinical symptoms of CHF; 2) Serum electrolytes, creatinine, BUN, urine protein 3) CBC with differential.; periodic 4) Blood pressure (if treating hypertension orsymptoms associated with hypotension arise)
Client Information - Give medication on an empty stomach unless otherwise instructed. Do notabruptly stop or reduce therapy without veterinarian's approval. Contact veterinarian if vomiting ordiarrhea persist or are severe or if animal's condition deteriorates.
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products:
Enalapril Maleate Tablets 1 mg, 2.5 mg, 5 mg, 10 mg, 20 mg; Enacard® (Merck); (Rx)
Approved for use in dogs.

Human-Approved Products:

Enalapril Maleate Tablets 2.5 mg, 5 mg, 10 mg, 20 mg; Vasotec® (Merck; Frosst-Canada); (Rx);Enalaprilat Injection (for IV use) equivalent to 1.25 mg/ml in 1 and 2 ml vials; Vasotec® I.V.(Merck); (Rx)
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