Doses - ESMOLOL HCL

Dogs:

For ultra-short acting beta blockade (for treating or assisting in treatment of ventricular arrhythmias):
a) 0.5 mg/kg IV slow load, then 50 - 200 micrograms/kg/min infusion. (Hamlin 1992)
b) Give incremental doses of 0.05 - 0.1 mg/kg boluses every 5 minutes to a maximum dose of 0.5 mg/kg; or as an infusion of 50 - 200 micrograms/kg/min. If arrhythmia conversion does not occur, then other drugs with negative inotropic effects (e.g. diltiazem or verapamil) may be given 30 minutes after esmolol administration. (Russell and Rush 1995)
Monitoring Parameters - 1) Blood Pressure; 2) ECG; 3) Heart Rate
Client Information - Esmolol should only be used in an in-patient setting where appropriate monitoring is available.
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products: None

Human-Approved Products:

Esmolol HCl Injection 10 mg/ml in 10 ml vials & 250 mg/ml in 10 ml amps;Brevibloc® (Ohmeda); (Rx)