Doses - EUTHANASIA AGENTS CONTAINING PENTOBARBITAL
Because different products have different concentrations, please refer to the informationprovided with the product in use.Dogs:
Pentobarbital sodium (as a single agent): Approximately 120 mg/kg for the first 4.5 kgof body weight, and 60 mg/kg for every 4.5 kg of body weight thereafter. Preferably administer IV.
Pentobarbital sodium with phenytoin (Beuthanasia®-D Special): 1 ml for each 4.5 kgof body weight
Cats: Pentobarbital sodium (as a single agent): Approximately 120 mg/kg for the first 4.5 kgof body weight, and 60 mg/kg for every 4.5 kg of body weight thereafter. Administer IV.
Pentobarbital sodium with phenytoin (Beuthanasia®-D Special): 1 ml for each 4.5 kgof body weight (not approved for use in this species)
Large Animals: (Note: must not be used in animals to be consumed by either humans or otheranimals). Depending on product concentration, most animals require 10 - 15 ml per 100 pounds ofbody weight.
Monitoring Parameters -
1) Respiratory, cardiac rate, corneal reflex
Client Information - Must be administered by an individual familiar with its use. Inform client observing euthanasia, that animal may give a terminal gasp after becoming unconscious.
Dosage Forms/Preparations - See other pentobarbital dosage forms under the main monograph for lower concentration products.
Pentobarbital Sodium for Injection (Euthanasia)
Sleepaway® (Fort Dodge) 260 mg/ml; 100 ml vials; C-II
Euthanasia-6® (Anthony) 390 mg/kg; 100 ml, 250 ml vials; C-II
Euthanasia Solution (Vet-Labs) 324 mg/ml; 100 ml vials; C-II
Pentobarbital Sodium 390 mg/ml/Phenytoin Sodium 50 mg/ml for Injection (Euthanasia)
Beuthanasia® -D Special (Schering) 100 ml vials; C-III
Pentobarbital Sodium 390 mg/ml/Lidocaine 20 mg/ml for Injection (Euthanasia) FP-3® (Vortech) 100ml vials; C-III
All products are controlled substances and require a prescription. Pentobarbital alone is a Class-II controlled substance, combination products are generally Class-III.
Another barbiturate combination product similar to Beuthanasia®-D or FP-3® is: Repose® (Syntex) which contains 400 mg/ml secobarbital and 25 mg/ml dibucaine. The suggested dose for euthanasia in dogs and cats is: 0.22 ml/kg body weight IV.
Dogs: 
Pentobarbital sodium (as a single agent): Approximately 120 mg/kg for the first 4.5 kgof body weight, and 60 mg/kg for every 4.5 kg of body weight thereafter. Preferably administer IV. Pentobarbital sodium with phenytoin (Beuthanasia®-D Special): 1 ml for each 4.5 kgof body weight
Cats: Pentobarbital sodium (as a single agent): Approximately 120 mg/kg for the first 4.5 kgof body weight, and 60 mg/kg for every 4.5 kg of body weight thereafter. Administer IV.
Pentobarbital sodium with phenytoin (Beuthanasia®-D Special): 1 ml for each 4.5 kgof body weight (not approved for use in this species)
Large Animals: (Note: must not be used in animals to be consumed by either humans or otheranimals). Depending on product concentration, most animals require 10 - 15 ml per 100 pounds ofbody weight.
Monitoring Parameters -
1) Respiratory, cardiac rate, corneal reflex
Client Information - Must be administered by an individual familiar with its use. Inform client observing euthanasia, that animal may give a terminal gasp after becoming unconscious.
Dosage Forms/Preparations - See other pentobarbital dosage forms under the main monograph for lower concentration products.
Pentobarbital Sodium for Injection (Euthanasia)
Sleepaway® (Fort Dodge) 260 mg/ml; 100 ml vials; C-II
Euthanasia-6® (Anthony) 390 mg/kg; 100 ml, 250 ml vials; C-II
Euthanasia Solution (Vet-Labs) 324 mg/ml; 100 ml vials; C-II
Pentobarbital Sodium 390 mg/ml/Phenytoin Sodium 50 mg/ml for Injection (Euthanasia)
Beuthanasia® -D Special (Schering) 100 ml vials; C-III
Pentobarbital Sodium 390 mg/ml/Lidocaine 20 mg/ml for Injection (Euthanasia) FP-3® (Vortech) 100ml vials; C-III
All products are controlled substances and require a prescription. Pentobarbital alone is a Class-II controlled substance, combination products are generally Class-III.
Another barbiturate combination product similar to Beuthanasia®-D or FP-3® is: Repose® (Syntex) which contains 400 mg/ml secobarbital and 25 mg/ml dibucaine. The suggested dose for euthanasia in dogs and cats is: 0.22 ml/kg body weight IV.