DESMOPRESSIN ACETATE
↪ Doses - DESMOPRESSIN ACETATE
Chemistry - A synthetic polypeptide related to arginine vasopressin (antidiuretic hormone), desmopressin acetate occurs as a fluffy white powder having a bitter taste. The commerciallyavailable nasal solution has HCl added and the pH is approximately 4. This...
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Doses - DEFEROXAMINE MESYLATE
↪ Description - DEFEROXAMINE MESYLATE
Dogs & Cats: In dogs at risk for, or exhibiting signs of severe iron toxicosis: a) Initiate ASAP or at least within 12 hours of ingestion; give as a constant rate infusion at 15 mg/kg/hour. More rapid infusion may precipitate arrhythmias or...
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DEFEROXAMINE MESYLATE
↪ Doses - DEFEROXAMINE MESYLATE
Chemistry - An iron chelating agent, deferoxamine mesylate occurs as a white to off-white powderthat is freely soluble in alcohol or water. Deferoxamine may also be known as desferoxaminemesylate or by the abbreviation DFO.Storage, Stability, Compatibility...
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Doses - DECOQUINATE
↪ Description - DECOQUINATE
Dogs: For coccidiosis: a) Prophylaxis: 50 mg/kg PO once daily (Matz 1995)Cattle: For prophylaxis of coccidiosis: a) Using the 6% premix: 0.5 mg/kg per day in feed for at least 28 days. (Penzhorn and Swan 1993) (McDougald and Roberson 1988) Goats: For...
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DECOQUINATE
↪ Doses - DECOQUINATE
Chemistry - A coccidiostat, decoquinate occurs as a cream to buff-colored fine amorphous powderhaving a slight odor. It is insoluble in water.Storage, Stability, Compatibility Decoquinate is reportedly incompatible with strong bases oroxidizing material. Follow label...
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Doses - DANTROLENE SODIUM
↪ Description - DANTROLENE SODIUM
Dogs: For treatment of functional urethral obstruction due to increased external urethral tone: a) 1 - 5 mg/kg PO q8h (Polzin and Osborne 1985), (Chew, DiBartola, and Fenner 1986) b) 3 - 15 mg/kg PO divided bid-tid (Morgan 1988) For adjunctive treatment of...
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DANTROLENE SODIUM
↪ Doses - DANTROLENE SODIUM
Chemistry - A hydantoin derivative which is dissimilar structurally and pharmacologically fromother skeletal muscle relaxant drugs, dantrolene sodium is a weak acid with a pKa of 7.5. It occursas an odorless, tasteless, orange, fine powder that is slightly...
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Doses - DANAZOL
Dogs: For adjunctive treatment of immune-mediated hemolytic anemia or thrombocytopenia: a) 5 mg/kg PO q12h; usually used for the first two weeks of therapy in combination withcorticosteroids. (Thompson 1994) b) 10 - 20 mg/kg/day (divided bid - tid) (Dougherty 1994) c) Initially, (in addition to...
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DANAZOL
↪ Doses - DANAZOL
Chemistry - A synthetic derivative of ethisterone (ethinyl testosterone), danazol occurs as a whiteto pale yellow, crystalline powder. It is practically insoluble in water and sparingly soluble inalcohol.Storage, Stability, Compatibility Danazol capsules should be stored...
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Doses - DACTINOMYCIN
↪ Description - DACTINOMYCIN
Also see the section on antineoplastic protocols found in the appendix. a) 0.7 mg/m2 IV every 7 days (Jacobs, Lumsden et al. 1992) Monitoring Parameters - 1) Efficacy; 2) Toxicity: including CBC with differential and platelets;hepatic function tests; check...
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DACTINOMYCIN
↪ Doses - DACTINOMYCIN
Chemistry - An antibiotic antineoplastic agent, dactinomycin (also known as actinomycin D)occurs as a bright red, crystalline powder. It is somewhat hygroscopic and soluble in water at 10°Cand slightly soluble at 37°C. The commercially available preparation...
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Doses - DACARBAZINE
↪ Description - DACARBAZINE
Dogs: For lymphoreticular neoplasms: a) 200 - 250 mg/m2 IV once daily for 5 days; repeat cycle every 21 days. (Jacobs, Lumsden et al. 1992) For soft tissue sarcomas: a) As part of the ADIC protocol: Dacarbazine 1000 mg/m2 IV drip over 6-8 hours, repeatevery 3...
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