Doses - BUPRENORPHINE HCL

Horses:

For neuroleptanalgesia:
a) 0.004 mg/kg IV (given with acepromazine 0.02 mg/kg) (Thurmon and Benson 1987)
b) 0.006 mg/kg IV (given with xylazine 0.07 mg/kg) (Thurmon and Benson 1987)

Rabbits & Rodents:

As an analgesic (for control of acute or chronic visceral pain):
a) Rabbits: 0.02 - 0.05 mg/kg SubQ or IM q6-12h; 0.5 mg/kg per rectum q12h
Rodents: 0.1 - 3 mg/kg IM or SubQ q6-12h (Huerkamp 1995)
Monitoring Parameters -

1) Analgesic efficacy

2) Respiratory status

3) Cardiac status
Client Information - This agent should be used in an inpatient setting or with direct professional supervision.
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products: None

Human-Approved Products:

Buprenorphine HCl for Injection: 0.324 mg/ml (equivalent to 0.3 mg/ml buprenorphine); 1 ml ampules; Buprenex® (Reckitt & Colman); (Rx)