Doses - NYSTATIN

Dogs:

For oral treatment of Candidal infections:
a) 100, 000 Units PO q6h (Kirk 1989)
b) 50, 000 - 150, 000 Units PO q8h (Jenkins and Boothe 1987)
c) 22, 000 Units/kg/day (Huber 1988b)

Cats:

For oral treatment of Candidal infections:
a) 100, 000 Units PO q6h (Kirk 1989)

Birds:

For crop mycosis and mycotic diarrhea (Candida albicans) in chickens and turkeys:
a) Feed at 50 grams per ton (Mycostatin®-20) or at 100 g/ton for 7-10 days. (Label directions; Mycostatin®-20¯Solvay)
For oropharyngeal Candidal infections:
a) In caged birds: 300, 000 Units/kg PO via crop tube or directly into mouth bid for 7-10days. Flocks may be treated using the veterinary product (Myco-20®) at 5 grams of
Myco-20 per pound of food. Add to either a cooked mash or other food. (Flammer1986)
b) For treatment of candidiasis after antibiotic or in conjunction with antibiotics: One ml ofthe 100, 000 U/ml suspension per 300 g body weight PO once, twice or 3 times daily for7-14 days. If treating mouth lesions do not give by gavage. Hand-fed babies shouldreceive antifungal therapy if being treated with antibiotics. (Clubb 1986)

Reptiles:

For susceptible infections:
a) For turtles with enteric yeast infections: 100, 000 IU/kg PO once daily for 10 days.(Gauvin 1993)
Monitoring Parameters -

1) Clinical efficacy
Client Information - Shake suspension well before administering.
Dosage Forms/Preparations/FDA Approval Status/Withholding Times - Veterinary-Approved Products: None

Human-Approved Products:

Nystatin Oral Suspension 100, 000 Units/ml in 5, 60, 473 and 480 ml bottles; Nilstat® (Lederle);
Mycostatin® (Apothecon); Nystex® (Savage); generic; (Rx)
Nystatin Bulk Powder: 50, 150, 500 million units, 1, 2 & 5 billion units; Nystatin® (Paddock);
Nilstat® (Lederle); (Rx)
Nystatin Oral Tablets 500, 000 Units; Nilstat® (Lederle); Mycostatin® (Apothecon); generic; (Rx)
Also available in oral troches, vaginal tablets, topical creams, powders and ointments o, p- DDD - see Mitotane