Doses - THIOTEPA
↪ Description - THIOTEPA
Dogs: For intracavitary use neoplastic effusions or systemically for adjunctive therapy of carcinomas: a) 0.2 - 0.5 mg/m2 intracavitary; IV. (Jacobs, Lumsden et al. 1992) Monitoring Parameters - 1) Efficacy; 2) CBC w/platelets Client Information - Clients must be...
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THIOTEPA
↪ Doses - THIOTEPA
Chemistry - An ethylene derivative alkylating agent antineoplastic, thiotepa occurs as fine, whitecrystalline flakes. The drug has a faint odor and is freely soluble in water or alcohol. Thiotepa mayalso be known as triethylenethiophosphoramide, TESPA, or TSPA.Storage,...
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Doses - THIOPENTAL SODIUM
↪ Description - THIOPENTAL SODIUM
Note: Atropine sulfate or glycopyrrolate are often administered prior to thiobarbiturateanesthesia to prevent parasympathetic side effects. Some clinicians question, however, whetherroutine administration of the anticholinergic agents are...
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THIOPENTAL SODIUM
↪ Doses - THIOPENTAL SODIUM
Chemistry - A thiobarbiturate, thiopental occurs as a bitter-tasting, white to off-white, crystallinepowder or a yellow-white hygroscopic powder. It is soluble in water (1 gram in 1.5 ml) and alcohol. Thiopental has a pKa of 7.6 and is a weak organic...
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Doses - THIOGUANINE
↪ Description - THIOGUANINE
For acute lymphocytic and granulocytic leukemia:Dogs: a) 40 mg/m2 PO once daily (q24 hours) for 4-5 days, then every 3rd day thereafter.(Jacobs, Lumsden et al. 1992)Cats: a) 25 mg/m2 PO once daily (q24 hours) for 1-5 days, then every 30 days thereafter...
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THIOGUANINE
↪ Doses - THIOGUANINE
Chemistry - A purine analog antineoplastic agent, thioguanine occurs as a pale yellow, odorless orpractically odorless, crystalline powder. It is insoluble in water or alcohol. Thioguanine may also beknown as 6- thioguanine, TG, 6-TG, or...
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Doses - THIAMYLAL SODIUM
↪ Description - THIAMYLAL SODIUM
Note: Atropine sulfate or glycopyrrolate are often administered prior to thiobarbiturate anesthesia toprevent parasympathetic side effects. Some clinicians question, however, whether routine administration of the anticholinergic agents are...
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THIAMYLAL SODIUM
↪ Doses - THIAMYLAL SODIUM
Note: Thiamylal is not available commercially at the time of this update but is still listed in the FDA's "Green Book". Most veterinary anestheisologists are recommending using thiopental asan alternative. The monograph remains in the VDH with the hope that the...
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Doses - THIAMINE HCL
↪ Description - THIAMINE HCL
Dogs: For thiamine deficiency: a) 5 - 50 mg IM, SQ, or IV (depending on formulation) (Phillips 1988b) b) 1 - 2 mg IM (Greene and Braund 1989) c) 2 mg/kg PO once daily (Davis 1985) d) 100 - 250 mg SQ bid for several days until regression of symptoms with...
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THIAMINE HCL
↪ Doses - THIAMINE HCL
VITAMIN B 1 Chemistry - A water-soluble B-complex vitamin, thiamine HCl occurs as bitter-tasting, white, smallhygroscopic crystals, or crystalline powder that has a characteristic yeast-like odor. Thiamine HClis freely soluble in water and slightly soluble in alcohol...
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Doses - THIACETARSEMIDE SODIUM
↪ Description - THIACETARSEMIDE SODIUM
Dogs: For elimination of adult heartworms: a) 2.2 mg/kg (0.22 ml/kg of a 1% solution) given twice a day for 2 days. Use an indwelling intravenous catheter or winged infusion set to avoid extravasation injuries.(Kittleson 1985) b) 2.2 mg/kg for 4...
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THIACETARSEMIDE SODIUM
↪ Doses - THIACETARSEMIDE SODIUM
Chemistry - A phenylarsenoxide, thiacetarsemide sodium is an organic arsenical compound. Thecommercially available injection is actually a combination of thiacetarsemide and p-arsenosobenzamide. It is available commercially in a 10 mg/ml (1%) solution and...
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