METHOTREXATE, METHOTREXATE SODIUM, Doses - METHOCARBAMOL, Veterinary Clinics, Diagnoses, Terms and Drug Handbook Online

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METHOTREXATE, METHOTREXATE SODIUM

↪ Doses - METHOTREXATE, METHOTREXATE SODIUM Chemistry - A folic acid antagonist, methotrexate is available commercially as the sodium salt. Itoccurs as a yellow powder that is soluble in water. Methotrexate sodium injection has a pH of 7.5-9. Methotrexate may also be known as Amethoptrin or... ↪ Read more

Doses - METHOCARBAMOL

↪ Description - METHOCARBAMOL Dogs: a) Injectable: For relief of moderate conditions: 44 mg/kg IV; For controlling severe effects of strychnine and tetanus: 55 - 220 mg/kg IV, do not exceed 330 mg/kg/day. Administer half the estimated dose rapidly, then wait until animal starts to relax... ↪ Read more

METHOCARBAMOL

↪ Doses - METHOCARBAMOL Chemistry - A centrally acting muscle relaxant related structurally to guaifenesin, methocarbamoloccurs as a fine, white powder with a characteristic odor. In water, it has a solubility 25 mg/ml. ThepH of commercial injection is approximately 4-5.Storage, Stability,... ↪ Read more

Doses - METHIONINE, DL-METHIONINE

↪ Description - METHIONINE, DL-METHIONINE Dogs: For urine acidification: a) In struvite dissolution therapy if diet and antimicrobials do not result in acid urine: 0.2 - 1.0 grams PO q8h (Lage, Polzin, and Zenoble 1988), (Kirk 1986)Cats: For urine acidification: a) 1000 - 1500 mg per day... ↪ Read more

METHIONINE, DL-METHIONINE

↪ Doses - METHIONINE, DL-METHIONINE Chemistry - A sulfur-containing amino acid, methionine occurs as a white, crystalline powder witha characteristic odor. One gram is soluble in about 30 ml of water and it is very slightly soluble inalcohol. 74.6 mg is equivalent to 1 mEq of... ↪ Read more

Doses - METHIMAZOLE

↪ Description - METHIMAZOLE Cats: For hyperthyroidism: a) Initially, 5 mg (not 5 mg/kg) PO q8h. Recheck serum thyroxine in 3 weeks, if little orno decrease, increase dose by 5 mg every 3 weeks until appropriate response occurs. During first 3 months of therapy, examine cat every 3 weeks to... ↪ Read more

METHIMAZOLE

↪ Doses - METHIMAZOLE Chemistry - A thioimidazole-derivative antithyroid drug, methimazole occurs as a white to palebuff crystalline powder, having a faint characteristic odor and a melting point of 144 -147°C. It isfreely soluble (1 gram in 5 ml) in water or alcohol.Storage,... ↪ Read more

Doses - METHENAMINE MANDELATE, METHENAMINE HIPPURATE

↪ Description - METHENAMINE MANDELATE, METHENAMINE HIPPURATE Dogs: a) Methenamine hippurate: 500 mg PO q12h; Methenamine mandelate: 10 - 20 mg/kg POq8-12h (Papich 1992)Cats: a) Methenamine hippurate: 250 mg PO q12h (Papich 1992) Monitoring Parameters - 1) Urine pH; 2) Efficacy Client... ↪ Read more

METHENAMINE MANDELATE, METHENAMINE HIPPURATE

↪ Doses - METHENAMINE MANDELATE, METHENAMINE HIPPURATE Chemistry - Methenamine is chemically unrelated to other anti-infective agents. It is commerciallyavailable in two salts, methenamine mandelate and methenamine hippurate. Methenamine mandelateoccurs as a white, crystalline powder and... ↪ Read more

Doses - MERCAPTOPURINE

↪ Description - MERCAPTOPURINE Dogs: For treatment of immune-mediated diseases or acute lymphocytic and granulocytic leukemias: a) 50 mg/m2 PO once daily (q24h) to effect, then every other day (q48h) or as needed.(Jacobs, Lumsden et al. 1992) Monitoring Parameters - 1) Hemograms (including... ↪ Read more

MERCAPTOPURINE

↪ Doses - MERCAPTOPURINE Chemistry - A purine analog, mercaptopurine occurs as a slightly yellow, crystalline powder. It isinsoluble in water and has a pKa of 7.6. Mercaptopurine may also be known as 6-mercaptopurineor 6-MP.Storage, Stability, Compatibility Mercaptopurine tablets should be... ↪ Read more

Doses - MEPHENYTOIN

↪ Description - MEPHENYTOIN Dogs: a) For adjunctive therapy of refractory seizures (not controlled with Phenobarbital orprimidone and potassium bromide): Initially, 10 mg/kg PO every 8 hours; increasedosage to achieve a nirvanol (active metabolite) blood level of 25 - 40... ↪ Read more