CYTARABINE
↪ Doses - CYTARABINE
Chemistry - A synthetic pyrimidine nucleoside antimetabolite, cytarabine occurs as an odorless, white to off-white, crystalline powder with a pKa of 4.35. It is freely soluble in water and slightlysoluble in alcohol. Cytarabine is also commonly known as ARA-C or...
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Doses - CYPROHEPTADINE HCL
↪ Description - CYPROHEPTADINE HCL
Dogs: As an antihistamine: a) 1.1 mg/kg PO q8-12h (Papich 1992) b) 0.3 - 2 mg/kg PO bid (Bevier 1990)Cats: As an appetite stimulant: a) 2 - 4 mg per cat PO once or twice daily (Davenport 1994) b) 2 mg per cat every 12 hours; may take up to 24 hours for...
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CYPROHEPTADINE HCL
↪ Doses - CYPROHEPTADINE HCL
Chemistry - An antihistamine that also possesses serotonin antagonist properties, cyproheptadine HCl occurs as a white to slightly yellow crystalline powder. Approximately 3.64 mg are soluble inone ml of water and 28.6 mg in one ml of alcohol.Storage, Stability,...
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Doses - CYCLOPHOSPHAMIDE
For more information, refer to the protocol references found in the appendix or otherprotocols found in numerous references, including: Handbook of Small Animal Practice (Ogilvie1988), (Cotter 1988), (Stann 1988a); Handbook of Small Animal Therapeutics (Rosenthal 1985); Current Veterinary Therapy...
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CYCLOPHOSPHAMIDE
↪ Doses - CYCLOPHOSPHAMIDE
Chemistry - A nitrogen-mustard derivative, cyclophosphamide occurs as a white, crystallinepowder that is soluble in water and alcohol. The commercially available injection has pH of 3 to 7.5. Cyclophosphamide may also be known as CPM, CTX or CYT.Storage,...
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Doses - CORTICOTROPIN (ACTH)
↪ Description - CORTICOTROPIN (ACTH)
Obtain specific information from the laboratory on sample handling and laboratorynormals for cortisol when doing ACTH stimulation tests. ACTH is quite unstable in unfrozenplasma.Dogs: ACTH Stimulation Test: a) Draw baseline blood sample for cortisol...
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CORTICOTROPIN (ACTH)
↪ Doses - CORTICOTROPIN (ACTH)
Chemistry - A 39 amino acid polypeptide, corticotropin is secreted from the anterior pituitary. Thefirst 24 amino acids (from the N-terminal end of the chain) define its biologic activity. Whilehuman, sheep, cattle and swine corticotropin have different...
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Doses - COLCHICINE
Colchicine may have some efficacy in the treatment of amyloidosis, but veterinary dosages areapparently unavailable at this time.Dogs: For the adjunctive treatment of hepatic cirrhosis/fibrosis: a) 0.025 - 0.03 mg/kg/day PO. Benefit is unproven. (Johnson and Sherding 1994) b) 0.025 mg/kg PO per...
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COLCHICINE
↪ Doses - COLCHICINE
Chemistry - An antigout drug possessing many other pharmacologic effects, colchicine occurs asa pale yellow, amorphous powder or scales. It is soluble in water and freely soluble in alcohol.Storage, Stability, Compatibility Colchicine tablets should be stored in tight,...
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Doses - CODEINE PHOSPHATE
↪ Description - CODEINE PHOSPHATE
Dogs: As an antitussive: a) 0.1 - 0.3 mg/kg PO q6-8h (Papich 1992) b) 1 - 2 mg/kg PO q6-12h (Fenner 1994) As an analgesic: a) 0.5 - 1 mg/kg PO q6-8h (Papich 1992) b) In combination with acetaminophen: Using a 60 mg codeine and 300 mg...
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CODEINE PHOSPHATE
↪ Doses - CODEINE PHOSPHATE
Chemistry - A phenanthrene-derivative opiate agonist, codeine is available as the base and threeseparate salts. Codeine base is slightly soluble in water and freely soluble in alcohol. Codeinephosphate occurs as fine, white, needle-like crystals or white,...
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Doses - CLOXACILLIN SODIUM, CLOXACILLIN BENZATHINE
↪ Description - CLOXACILLIN SODIUM, CLOXACILLIN BENZATHINE
Author's (Plumb) note: Injectable form is not available in the U.S.A.Dogs: For susceptible infections: a) 20 - 40 mg/kg PO q8h (Vaden and Papich 1995) b) 10 - 15 mg/kg q6h PO, IV, or IM (Greene 1984) c) For Staph. diskospondylitis...
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