Doses - METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM

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Doses - METHOTREXATE, METHOTREXATE SODIUM

↪ Description - METHOTREXATE, METHOTREXATE SODIUM Dosages of methotrexate sodium are expressed in terms of methotrexate as are the dosageforms. For more information, refer to the protocol references found in the appendix or otherprotocols found in other small animal medicine texts. Dogs: ... ↪ Read more

METHOTREXATE, METHOTREXATE SODIUM

↪ Doses - METHOTREXATE, METHOTREXATE SODIUM Chemistry - A folic acid antagonist, methotrexate is available commercially as the sodium salt. Itoccurs as a yellow powder that is soluble in water. Methotrexate sodium injection has a pH of 7.5-9. Methotrexate may also be known as Amethoptrin or... ↪ Read more

Doses - METHOCARBAMOL

↪ Description - METHOCARBAMOL Dogs: a) Injectable: For relief of moderate conditions: 44 mg/kg IV; For controlling severe effects of strychnine and tetanus: 55 - 220 mg/kg IV, do not exceed 330 mg/kg/day. Administer half the estimated dose rapidly, then wait until animal starts to relax... ↪ Read more

METHOCARBAMOL

↪ Doses - METHOCARBAMOL Chemistry - A centrally acting muscle relaxant related structurally to guaifenesin, methocarbamoloccurs as a fine, white powder with a characteristic odor. In water, it has a solubility 25 mg/ml. ThepH of commercial injection is approximately 4-5.Storage, Stability,... ↪ Read more

Doses - METHIONINE, DL-METHIONINE

↪ Description - METHIONINE, DL-METHIONINE Dogs: For urine acidification: a) In struvite dissolution therapy if diet and antimicrobials do not result in acid urine: 0.2 - 1.0 grams PO q8h (Lage, Polzin, and Zenoble 1988), (Kirk 1986)Cats: For urine acidification: a) 1000 - 1500 mg per day... ↪ Read more

METHIONINE, DL-METHIONINE

↪ Doses - METHIONINE, DL-METHIONINE Chemistry - A sulfur-containing amino acid, methionine occurs as a white, crystalline powder witha characteristic odor. One gram is soluble in about 30 ml of water and it is very slightly soluble inalcohol. 74.6 mg is equivalent to 1 mEq of... ↪ Read more

Doses - METHIMAZOLE

↪ Description - METHIMAZOLE Cats: For hyperthyroidism: a) Initially, 5 mg (not 5 mg/kg) PO q8h. Recheck serum thyroxine in 3 weeks, if little orno decrease, increase dose by 5 mg every 3 weeks until appropriate response occurs. During first 3 months of therapy, examine cat every 3 weeks to... ↪ Read more

METHIMAZOLE

↪ Doses - METHIMAZOLE Chemistry - A thioimidazole-derivative antithyroid drug, methimazole occurs as a white to palebuff crystalline powder, having a faint characteristic odor and a melting point of 144 -147°C. It isfreely soluble (1 gram in 5 ml) in water or alcohol.Storage,... ↪ Read more

Doses - METHENAMINE MANDELATE, METHENAMINE HIPPURATE

↪ Description - METHENAMINE MANDELATE, METHENAMINE HIPPURATE Dogs: a) Methenamine hippurate: 500 mg PO q12h; Methenamine mandelate: 10 - 20 mg/kg POq8-12h (Papich 1992)Cats: a) Methenamine hippurate: 250 mg PO q12h (Papich 1992) Monitoring Parameters - 1) Urine pH; 2) Efficacy Client... ↪ Read more

METHENAMINE MANDELATE, METHENAMINE HIPPURATE

↪ Doses - METHENAMINE MANDELATE, METHENAMINE HIPPURATE Chemistry - Methenamine is chemically unrelated to other anti-infective agents. It is commerciallyavailable in two salts, methenamine mandelate and methenamine hippurate. Methenamine mandelateoccurs as a white, crystalline powder and... ↪ Read more

Doses - MERCAPTOPURINE

↪ Description - MERCAPTOPURINE Dogs: For treatment of immune-mediated diseases or acute lymphocytic and granulocytic leukemias: a) 50 mg/m2 PO once daily (q24h) to effect, then every other day (q48h) or as needed.(Jacobs, Lumsden et al. 1992) Monitoring Parameters - 1) Hemograms (including... ↪ Read more

MERCAPTOPURINE

↪ Doses - MERCAPTOPURINE Chemistry - A purine analog, mercaptopurine occurs as a slightly yellow, crystalline powder. It isinsoluble in water and has a pKa of 7.6. Mercaptopurine may also be known as 6-mercaptopurineor 6-MP.Storage, Stability, Compatibility Mercaptopurine tablets should be... ↪ Read more