Doses - PHENYLBUTAZONE
Dogs: a) 14 mg/kg PO tid initially (maximum of 800 mg/day regardless of weight), titrate dose tolowest effective dose (Package Insert; Butazolidin® - Coopers) b) For analgesia/phlebitis: 3-5 mg/kg PO tid; for analgesia/spinal disorders: 8-10 mg/kg PO tid (max. 800 mg/day); for...
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PHENYLBUTAZONE
↪ Doses - PHENYLBUTAZONE
Chemistry - A synthetic pyrazolone derivative related chemically to aminopyrine, phenylbutazoneoccurs as a white to off-white, odorless crystalline powder that has a pKa of 4.5. It is very slightlysoluble in water and 1 gram will dissolve in 28 ml of alcohol. It is...
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Doses - PHENOXYBENZAMINE HCL
↪ Description - PHENOXYBENZAMINE HCL
Note:Because the only dosage form available is a 10 mg capsule, doses should be roundedto the nearest 2.5 mg dose when possible.Dogs: Treatment of detrusor areflexia: a) 5 mg - 15 mg PO once daily. (Chew, DiBartola, and Fenner 1986) b) Initially, 10 mg...
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PHENOXYBENZAMINE HCL
↪ Doses - PHENOXYBENZAMINE HCL
Chemistry - An alpha-adrenergic blocking agent, phenoxybenzamine HCl occurs as an odorless, white crystalline powder with a melting range of 136°-141° and a pKa of 4.4. Approximately 40 mgis soluble in 1 ml of water and 167 mg is soluble in 1 ml of...
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Doses - PHENOBARBITAL SODIUM, PHENOBARBITAL
↪ Description - PHENOBARBITAL SODIUM, PHENOBARBITAL
Dogs: For treatment of idiopathic epilepsy: a) 1 - 2 mg/kg PO bid initially, then monitor and adjust dosage. Some require up to 16mg/kg/day. (Morgan 1988) b) 5 - 16 mg/kg/day divided bid or tid (Bunch 1986) c) Initially, 2.5 mg/kg PO bid,...
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PHENOBARBITAL SODIUM, PHENOBARBITAL
↪ Doses - PHENOBARBITAL SODIUM, PHENOBARBITAL
Chemistry - Phenobarbital, a barbiturate, occurs as white, glistening, odorless, small crystals or asa white, crystalline powder with a melting point of 174°-178°C and a pKa of 7.41. One gram issoluble in approximately 1000 ml of...
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Doses - PENTOBARBITAL SODIUM
↪ Description - PENTOBARBITAL SODIUM
Dogs: a) For adjunctive therapy for ulcerative dermatosis of Shelties and Collies: 400 mg (onetablet) PO once daily or every other day if vomiting is a problem. If it can be reformulatedinto capsules, divide daily dose and give up to 3 times daily....
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Doses - PENTOBARBITAL SODIUM
↪ Description - PENTOBARBITAL SODIUM
Note: In order to avoid possible confusion, doses used for euthanasia are listed separatelyunder the monograph for pentobarbital euthanasia solutions.Dogs: As a sedative: a) 2 - 4 mg/kg IV (Kirk 1986) b) 2 - 4 mg/kg PO q6h (Davis 1985a) For anesthesia:...
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PENTOBARBITAL SODIUM
↪ Doses - PENTOBARBITAL SODIUM
(Note: Combinations of pentobarbital with other agents (e.g., phenytoin) for euthanasia have aseparate monograph listed under Euthanasia Agents) Chemistry - Pentobarbital sodium occurs as odorless, slightly bitter tasting, white, crystallinepowder or granules....
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Doses - PENICILLIN V POTASSIUM
↪ Description - PENICILLIN V POTASSIUM
Dogs: For analgesia: a) Initially 1.65 mg/kg; up to 3.3 mg/kg IM. Duration of effect generally lasts 3 hours. Ifdose is repeated, use different injection site. (Package Insert; Talwin®-V - Winthrop) b) 0.2 - 0.5 mg/kg IM prn (Morgan 1988) c) 0.5...
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Doses - PENICILLIN V POTASSIUM
↪ Description - PENICILLIN V POTASSIUM
Dogs: For susceptible infections: a) 5.5 - 11 mg/kg PO q6-8h (Aronson and Aucoin 1989) b) 10 mg/kg (listed as penicillin V) PO q8h (Kirk 1989)Cats: For susceptible infections: a) 5.5 - 11 mg/kg PO q6-8h (Aronson and Aucoin 1989) b) 10 mg/kg (listed...
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PENICILLIN V POTASSIUM
↪ Doses - PENICILLIN V POTASSIUM
For general information on the penicillins, including adverse effects, contraindications, overdosage, drug interactions and monitoring parameters, refer to the monograph: Penicillins, General Information. Chemistry - A natural penicillin, penicillin V is...
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